D Rey1, Y Obadia, H Tissot-Dupont, D Raoult. 1. Regional Center for Disease Control of South-Eastern France (ORS PACA), 23 rue Stanislas, Torrents, 13006 Marseille, France. rey@marseille.inserm.fr
Abstract
OBJECTIVES: To estimate the seroprevalence of antibodies to Coxiella burnetii among pregnant women and to assess the effect of Q fever on pregnancy outcome. STUDY DESIGN: Anonymous seroprevalence survey between March and May 1996 in all gynecological and obstetrical medical departments of South Eastern France. Women were included irrespective of pregnancy outcome (N=12,716, response rate=96.1%). RESULTS: The seroprevalence rate was 0.15% with a global prevalence and a prevalence of recent or chronic infections, respectively, two and three times higher among women who had a spontaneous abortion than among those who delivered although the differences were not statistically significant. The highest proportion of preterm births (6.8%) was found in high prevalence areas (0.57%). CONCLUSION: The seroprevalence was higher than expected but data were not sufficient to confirm the suspected negative impact of Q fever on pregnancy outcome.
OBJECTIVES: To estimate the seroprevalence of antibodies to Coxiella burnetii among pregnant women and to assess the effect of Q fever on pregnancy outcome. STUDY DESIGN: Anonymous seroprevalence survey between March and May 1996 in all gynecological and obstetrical medical departments of South Eastern France. Women were included irrespective of pregnancy outcome (N=12,716, response rate=96.1%). RESULTS: The seroprevalence rate was 0.15% with a global prevalence and a prevalence of recent or chronic infections, respectively, two and three times higher among women who had a spontaneous abortion than among those who delivered although the differences were not statistically significant. The highest proportion of preterm births (6.8%) was found in high prevalence areas (0.57%). CONCLUSION: The seroprevalence was higher than expected but data were not sufficient to confirm the suspected negative impact of Q fever on pregnancy outcome.
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