Identification and sequence analysis of the core protein genes of bovine adenovirus 2.

The DNA sequence of the genome of bovine adenovirus type 2 (BAdV-2) was determined between map units 42.5 and 50. By sequence analysis and homology search, the genes of five structural proteins were identified within this region: the penton base protein (III; partial sequence), the major core protein precursor (pVII), the minor core protein (V), the mu core protein precursor (pX) and the hexon associated protein precursor (pVI; partial sequence). The putative polypeptides were compared to their known counterparts from other adenoviruses. The existence of protein V and the presence and structure of certain protease cleavage recognition sites confirmed BAdV-2 as a member of the genus Mastadenovirus.