Literature DB >> 11073659

Formation of 9,10-unsaturation in the mitomycins: facile fragmentation of beta-alkyl-beta-aryl-alpha-oxo-gamma-butyrolactones.

F E Ziegler1, M Y Berlin, K Lee, A R Looker.   

Abstract

A facile fragmentation of beta-alkyl-beta-aryl-alpha-oxo-gamma-butyrolactones is reported. A study to assist in the elucidation of the mechanism of the reaction is also revealed.

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Year:  2000        PMID: 11073659     DOI: 10.1021/ol000245g

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis of an advanced intermediate en route to the mitomycin natural products.

Authors:  Amie L Williams; Jayasree M Srinivasan; Jeffrey N Johnston
Journal:  Org Lett       Date:  2006-12-21       Impact factor: 6.005

2.  Mitomycins syntheses: a recent update.

Authors:  Jean-Christophe Andrez
Journal:  Beilstein J Org Chem       Date:  2009-07-08       Impact factor: 2.883

  2 in total

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