| Literature DB >> 11073639 |
M del Fresno1, A El-Faham, L A Carpino, M Royo, F Albericio.
Abstract
The guanidine moiety is an important motif present in many biologically active compounds. Fully substituted guanidines are of key importance for the development of bioactive molecules. The present paper reports on an efficient procedure for the direct solid-phase conversion of amines to fully substituted guanidines under very mild conditions.Entities:
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Year: 2000 PMID： 11073639 DOI： 10.1021/ol006322p
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005