| Literature DB >> 1107310 |
Abstract
The direction of chromosome replication in a temperature-sensitive initiation mutant of Escherichia coli (CT28) is shown autoradiographically to be bidirectional. This mode of replication persists even when the rate of replication is reduced by slow growth in succinate minimal medium or in the presence of chloramphenicol. Therefore, although the rate of replication can be affected by certain physiological stimuli, the topology of replication need not be.Entities:
Mesh:
Substances:
Year: 1976 PMID: 1107310 PMCID: PMC233369 DOI: 10.1128/jb.125.1.346-352.1976
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490