Literature DB >> 11072948

Lithium-induced increase in human brain grey matter.

G J Moore, J M Bebchuk, I B Wilds, G Chen, H K Manji, H K Menji.   

Abstract

Rodent studies have shown that lithium exerts neurotrophic or neuroprotective effects. We used three-dimensional magnetic resonance imaging and brain segmentation to study pharmacologically-induced increases in grey matter volume with chronic lithium use in patients with bipolar mood disorder. Grey-matter volume increased after 4 weeks of treatment. The increases in grey matter probably occurred because of neurotrophic effects.

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Year:  2000        PMID： 11072948     DOI： 10.1016/s0140-6736(00)02793-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  138 in total

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Review 7.  A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force.

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8.  Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.

Authors:  Daniel P Dickstein; Kenneth E Towbin; Jan Willem Van Der Veen; Brendan A Rich; Melissa A Brotman; Lisa Knopf; Laura Onelio; Daniel S Pine; Ellen Leibenluft
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9.  Predictors of lithium response in bipolar disorder.

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Authors:  Lei Wang; Daniel Mamah; Michael P Harms; Meghana Karnik; Joseph L Price; Mokhtar H Gado; Paul A Thompson; Deanna M Barch; Michael I Miller; John G Csernansky
Journal:  Biol Psychiatry       Date:  2008-09-23       Impact factor: 13.382
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