| Literature DB >> 11072119 |
S G Kolaeva1, T P Semenova, I M Santalova, D A Moshkov, I A Anoshkina, V Golozubova.
Abstract
The effects of kyotorphin (KTP), a dipeptide (L-Tyr-L-Arg), on the level of sensory attention to stimuli of different modalities in rats and the exploratory behavior in goldfish were investigated. In both cases KTP was found to suppress the exploratory activity. When 5-HTP, a precursor of serotonin synthesis, is activated the inhibitory effects of KTP increased. It is assumed that the regulatory effect of KTP on the exploratory behavior of animals is mediated by the monoaminergic (neurotransmitting) brain systems, as distinct from its analgetic effects, which are mediated by the opioid brain systems.Entities:
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Year: 2000 PMID： 11072119 DOI： 10.1016/s0196-9781(00)00275-8
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750