| Literature DB >> 11072087 |
A J Parsian1, J E Sheren, T Y Tao, P C Goswami, R Malyapa, R Van Rheeden, M S Watson, C R Hunt.
Abstract
The human heat-inducible Hsp70B and Hsp70B' genes were co-localized to 1q23.1 by in situ hybridization. However, though transcripts from Hsp70B could be detected in heat-shocked cells, DNA sequence analyses of both the gene and cDNA copies of the mRNA indicate the gene is non-functional. Moreover, mouse homologues of Hsp70B/B' were not detected by Southern blot analysis, suggesting Hsp70B/B' arose from either Hsp70-1or Hsp70-2 after the divergence of mice and humans.Entities:
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Year: 2000 PMID： 11072087 DOI： 10.1016/s0167-4781(00)00203-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002