Literature DB >> 11072085

Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene.

J N Schofield1, T W Rademacher.   

Abstract

Here we report the structure of the human glycosylphosphatidylinositol phospholipase D1 gene, which covers at least 80 kb on chromosome 6p22. The gene comprises 25 exons and encodes a 5.8 kb mRNA, which was detected only in the liver. Southern blot analysis shows that the human genome contains only one GPLD gene and we could only detect one of the two previously reported cDNAs.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11072085     DOI： 10.1016/s0167-4781(00)00194-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.

Authors:  H Xiaotong; Melanie-Jane Hannocks; Ian Hampson; Georg Brunner
Journal:  Clin Exp Metastasis       Date:  2002       Impact factor: 5.150

Review 2.  Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer.

Authors:  Ronald C Bruntz; Craig W Lindsley; H Alex Brown
Journal:  Pharmacol Rev       Date:  2014-10       Impact factor: 25.468

3.  The Clinical Significance of Glycoprotein Phospholipase D Levels in Distinguishing Early Stage Latent Autoimmune Diabetes in Adults and Type 2 Diabetes.

Authors:  Wen Qin; Yu-Zhen Liang; Bao-Yu Qin; Jia-Li Zhang; Ning Xia
Journal:  PLoS One       Date:  2016-06-28       Impact factor: 3.240

4.  Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis.

Authors:  Takahiro Nishio; Yukinori Koyama; Xiao Liu; Sara B Rosenthal; Gen Yamamoto; Hiroaki Fuji; Jacopo Baglieri; Na Li; Laura N Brenner; Keiko Iwaisako; Kojiro Taura; James S Hagood; Nicholas F LaRusso; Tapan K Bera; Ira Pastan; David A Brenner; Tatiana Kisseleva
Journal:  Proc Natl Acad Sci U S A       Date:  2021-07-20       Impact factor: 12.779

5.  A transcription map of the 6p22.3 reading disability locus identifying candidate genes.

Authors:  Eric R Londin; Haiying Meng; Jeffrey R Gruen
Journal:  BMC Genomics       Date:  2003-06-30       Impact factor: 3.969

6.  Insulin-mimicking bioactivities of acylated inositol glycans in several mouse models of diabetes with or without obesity.

Authors:  Susumu Suzuki; Chitose Suzuki; Yoshinori Hinokio; Yasushi Ishigaki; Hideki Katagiri; Makoto Kanzaki; Viatcheslav N Azev; Nilanjana Chakraborty; Marc d'Alarcao
Journal:  PLoS One       Date:  2014-06-27       Impact factor: 3.240
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.