Literature DB >> 11071323

Pre-operative ultrasonography guiding minimal, selective surgical approach in primary hyperparathyroidism.

O A Preventza1, S Yang, J J Karo, A Lobocki, V Mittal, D W Sims, S Young.   

Abstract

BACKGROUND: The traditional surgical approach for the treatment of primary hyperparathyroidism (HPT) has been routine bilateral surgical exploration. Our aim was to evaluate pre-operative ultrasonography (U/S) in altering our practice to selective unilateral neck exploration. PATIENTS AND METHODS: A retrospective study was conducted involving 53 patients who had parathyroidectomy over a 5-year period (1989-1994), 41 of whom with the diagnosis of HPT had pre-operative neck U/S.
RESULTS: Thirty-eight patients had a single adenoma, one had parathyroid cancer, and two had multiple adenomas. Thirty-six of 41 (88%) patients were true positives, two (5%) false positives, two (5%) false negatives and one (2%) was true negative. Based on the surgeon's personal preference and U/S results, 21/41 (51%) of patients had bilateral and 20/41 (49%) had unilateral neck exploration. All the 41 patients had resolution of the hypercalcemia postoperatively. Eighteen of 38 (47%) patients with a single adenoma had bilateral neck exploration and only in two patients was this necessary.
CONCLUSIONS: Patients undergoing parathyroid surgery for HPT should have preoperative U/S and, if a single enlarged parathyroid gland is found, unilateral U/S guided neck exploration is safe and economical. In all the other patients, bilateral exploration is the preferred approach.

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Year:  2000        PMID: 11071323

Source DB:  PubMed          Journal:  Int Surg        ISSN: 0020-8868


  1 in total

1.  Accuracy of surgeon-performed ultrasound in parathyroid localization.

Authors:  Russell Van Husen; Lawrence T Kim
Journal:  World J Surg       Date:  2004-11       Impact factor: 3.352

  1 in total

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