Literature DB >> 11071251

Osteoclast differentiation factor in human osteosarcoma cell line.

K Kinpara1, M Mogi, M Kuzushima, A Togari.   

Abstract

A sensitive sandwich enzyme-linked immunosorbent assay (ELISA) for human osteoclast differentiation factor (ODF/RANKL/ OPGL/TRANCE) utilizing a polyclonal antibody that recognizes both human soluble ODF and mouse ODF in combination with a osteoclasogenesis inhibitory factor (OCIF/OPG) was developed. We can quantify the ODF level in not only human ODF (detection limit: 0.05 ng/ml), but also mouse ODF by virtue of cross-reactivity. Employing this assay system, we demonstrated that ODF is constitutively present as a membrane-bound form in both the human osteosarcoma cell lines, MG-63, HOS and SaOS-2, and the mouse osteoblastic cell line MC3T3-E1.

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Year:  2000        PMID： 11071251     DOI： 10.1080/01971520009349540

Source DB:  PubMed          Journal:  J Immunoassay        ISSN： 0197-1522


  9 in total

1.  Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading.

Authors:  Lidan You; Sara Temiyasathit; Peling Lee; Chi Hyun Kim; Padmaja Tummala; Wei Yao; Wade Kingery; Amanda M Malone; Ronald Y Kwon; Christopher R Jacobs
Journal:  Bone       Date:  2007-09-26       Impact factor: 4.398

Review 2.  Bone microenvironment signals in osteosarcoma development.

Authors:  Arantzazu Alfranca; Lucia Martinez-Cruzado; Juan Tornin; Ander Abarrategi; Teresa Amaral; Enrique de Alava; Pablo Menendez; Javier Garcia-Castro; Rene Rodriguez
Journal:  Cell Mol Life Sci       Date:  2015-05-03       Impact factor: 9.261

Review 3.  Galectin-3 in bone tumor microenvironment: a beacon for individual skeletal metastasis management.

Authors:  Kosei Nakajima; Dong Hyo Kho; Takashi Yanagawa; Melissa Zimel; Elisabeth Heath; Victor Hogan; Avraham Raz
Journal:  Cancer Metastasis Rev       Date:  2016-06       Impact factor: 9.264

4.  Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis.

Authors:  Lucia Mancini; Mark J Paul-Clark; Guglielmo Rosignoli; Robert Hannon; Jo E Martin; Ian Macintyre; Mauro Perretti
Journal:  Am J Pathol       Date:  2007-03       Impact factor: 4.307

5.  Expression of receptor activator of NF-kappaB ligand (RANKL) mRNA in human multiple myeloma cells.

Authors:  Ulrike Heider; Ivana Zavrski; Christian Jakob; Katharina Bängeroth; Claudia Fleissner; Corinna Langelotz; Kurt Possinger; Lorenz C Hofbauer; Volker Viereck; Orhan Sezer
Journal:  J Cancer Res Clin Oncol       Date:  2004-06-15       Impact factor: 4.553

6.  The biological effects of fibrin-binding synthetic oligopeptides derived from fibronectin on osteoblast-like cells.

Authors:  Yun-Jeong Kim; Yoon-Jeong Park; Yong-Moo Lee; In-Chul Rhyu; Young Ku
Journal:  J Periodontal Implant Sci       Date:  2012-08-31       Impact factor: 2.614

7.  The molecular pathogenesis of osteosarcoma: a review.

Authors:  Matthew L Broadhead; Jonathan C M Clark; Damian E Myers; Crispin R Dass; Peter F M Choong
Journal:  Sarcoma       Date:  2011-04-13

8.  Dendritic and mast cell involvement in the inflammatory response to primary malignant bone tumours.

Authors:  Y Inagaki; E Hookway; K A Williams; A B Hassan; U Oppermann; Y Tanaka; E Soilleux; N A Athanasou
Journal:  Clin Sarcoma Res       Date:  2016-08-01

Review 9.  The Role of Pre-Clinical 3-Dimensional Models of Osteosarcoma.

Authors:  Hannah L Smith; Stephen A Beers; Juliet C Gray; Janos M Kanczler
Journal:  Int J Mol Sci       Date:  2020-07-31       Impact factor: 5.923
  9 in total

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