| Literature DB >> 11070436 |
M Burke1, S Zinkovsky, M A Abrantes, W Riley.
Abstract
The authors describe an 11-year-old girl with duplication of a pituitary gland and hypertelorism. Of the 14 cases described to date, only 2 others have lacked associated major facial or oral anomalies. Two separate glands, respective stalks and hypothalamic enlargement were incidentally found on MR imaging performed to evaluate the patient's complaint of anosmia. A tortuous fusiform dilatation of one pericallosal artery was also discovered. A review of hypophyseal embryogenesis is presented. It is now evident that duplication of the pituitary can occur without other major dysmorphias. This may infer that notochord/prochordal plate deficits are not a prerequisite for hypophyseal duplication. Copyright 2000 S. Karger AG, Basel.Entities:
Mesh:
Year: 2000 PMID: 11070436 DOI: 10.1159/000028983
Source DB: PubMed Journal: Pediatr Neurosurg ISSN: 1016-2291 Impact factor: 1.162