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Literature DB >> 11069102

Metabolic control: a new solution to an old problem.

Abstract

The phenomenon whereby the presence of oxygen regulates the rate of glucose metabolism was first described by Louis Pasteur. A novel mechanism has now been discovered, involving the AMP-activated protein kinase cascade, that can account for the Pasteur effect in ischaemic heart muscle.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2000 PMID： 11069102 DOI： 10.1016/s0960-9822(00)00744-2

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

14 in total

Review 1. Physiological and pathological responses to hypoxia.

Authors: Carine Michiels
Journal: Am J Pathol Date: 2004-06 Impact factor: 4.307

Review 2. Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

Authors: R Brooks Robey; Judith Weisz; Nancy B Kuemmerle; Anna C Salzberg; Arthur Berg; Dustin G Brown; Laura Kubik; Roberta Palorini; Fahd Al-Mulla; Rabeah Al-Temaimi; Annamaria Colacci; Chiara Mondello; Jayadev Raju; Jordan Woodrick; A Ivana Scovassi; Neetu Singh; Monica Vaccari; Rabindra Roy; Stefano Forte; Lorenzo Memeo; Hosni K Salem; Amedeo Amedei; Roslida A Hamid; Graeme P Williams; Leroy Lowe; Joel Meyer; Francis L Martin; William H Bisson; Ferdinando Chiaradonna; Elizabeth P Ryan
Journal: Carcinogenesis Date: 2015-06 Impact factor: 4.944

Metabolic control: a new solution to an old problem.

Review 1. Physiological and pathological responses to hypoxia.

Review 2. Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

3. Oligomycin-induced bioenergetic adaptation in cancer cells with heterogeneous bioenergetic organization.

Review 4. Hypoxia and metabolic properties of hematopoietic stem cells.

5. Cellular Glycolysis and The Differential Survival of Lung Fibroblast and Lung Carcinoma Cell Lines.

6. Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility.

7. One-electron reduction of 6-hydroxydopamine quinone is essential in 6-hydroxydopamine neurotoxicity.

Review 8. Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression.

9. Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors.

10. Expression patterns of protein kinases correlate with gene architecture and evolutionary rates.