Literature DB >> 11062600

Recent advances in the management of hypertension in the elderly.

F J Gennari1, A S Gennari.   

Abstract

Important new advances have occurred in our understanding and approach to management of high blood pressure in the elderly. New clinical trials have re-emphasized the risk of development of cardiovascular and cerebrovascular complications associated with isolated elevations in systolic blood pressure as well as the safety and efficacy of interventions to reduce blood pressure. These trials have shown that systolic blood pressure can be reduced by interventions such as weight loss, restriction of dietary sodium intake, and drugs. In several new trials, the long-acting dihydropyridine calcium channel blockers have been found to be safe and effective in these patients but not superior to other drugs. As in younger individuals with hypertension, drug therapy should be targeted to address comorbidity. Education of primary care physicians concerning these new findings is the next step in reducing the morbidity and mortality of this common problem in the elderly.

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Year:  2000        PMID: 11062600     DOI: 10.1007/s11906-996-0039-2

Source DB:  PubMed          Journal:  Curr Hypertens Rep        ISSN: 1522-6417            Impact factor:   5.369


  40 in total

Review 1.  Prevention of falls among the elderly.

Authors:  M E Tinetti; M Speechley
Journal:  N Engl J Med       Date:  1989-04-20       Impact factor: 91.245

2.  Double-blind randomised trial of modest salt restriction in older people.

Authors:  F P Cappuccio; N D Markandu; C Carney; G A Sagnella; G A MacGregor
Journal:  Lancet       Date:  1997-09-20       Impact factor: 79.321

3.  Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. Systolic Hypertension in China (Syst-China) Collaborative Group.

Authors:  L Liu; J G Wang; L Gong; G Liu; J A Staessen
Journal:  J Hypertens       Date:  1998-12       Impact factor: 4.844

4.  Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.

Authors:  J A Staessen; R Fagard; L Thijs; H Celis; G G Arabidze; W H Birkenhäger; C J Bulpitt; P W de Leeuw; C T Dollery; A E Fletcher; F Forette; G Leonetti; C Nachev; E T O'Brien; J Rosenfeld; J L Rodicio; J Tuomilehto; A Zanchetti
Journal:  Lancet       Date:  1997-09-13       Impact factor: 79.321

Review 5.  Summary of randomized trials of angiotensin converting enzyme inhibitors.

Authors:  S Yusuf; E Lonn; J Bosch; H Gerstein
Journal:  Clin Exp Hypertens       Date:  1999 Jul-Aug       Impact factor: 1.749

6.  There are no racial, age, sex, or weight differences in the effect of salt on blood pressure in salt-sensitive hypertensive patients.

Authors:  S G Chrysant; M R Weir; A B Weder; D A McCarron; M Canossa-Terris; J D Cohen; R F Mennella; L W Kirkegaard; A J Lewin; M H Weinberger
Journal:  Arch Intern Med       Date:  1997-11-24

7.  Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

Authors: 
Journal:  JAMA       Date:  1991-06-26       Impact factor: 56.272

8.  The long-term prognostic significance of repeated blood pressure measurements in the elderly: SPAA (Studio sulla Pressione Arteriosa nell'Anziano) 10-year follow-up.

Authors:  C Alli; F Avanzini; G Bettelli; F Colombo; V Torri; G Tognoni
Journal:  Arch Intern Med       Date:  1999-06-14

9.  Are beta-blockers efficacious as first-line therapy for hypertension in the elderly? A systematic review.

Authors:  F H Messerli; E Grossman; U Goldbourt
Journal:  JAMA       Date:  1998-06-17       Impact factor: 56.272

Review 10.  Salt sensitivity of blood pressure in humans.

Authors:  M H Weinberger
Journal:  Hypertension       Date:  1996-03       Impact factor: 10.190

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  1 in total

Review 1.  Drug interactions with angiotensin receptor blockers: a comparison with other antihypertensives.

Authors:  Thomas Unger; Elena Kaschina
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

  1 in total

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