Literature DB >> 11062532

Decoding calcium signals involved in cardiac growth and function.

N Frey1, T A McKinsey, E N Olson.   

Abstract

Calcium is central in the regulation of cardiac contractility, growth and gene expression. Variations in the amplitude, frequency and compartmentalization of calcium signals are decoded by calcium/calmodulin-dependent enzymes, ion channels and transcription factors. Understanding the circuitry for calcium signaling creates opportunities for pharmacological modification of cardiac function.

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Year:  2000        PMID： 11062532     DOI： 10.1038/81321

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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