Literature DB >> 11060594

Visceral nociception.

K N Westlund1.   

Abstract

Visceral pain is of great concern to the medical community because it remains particularly resistant to current clinical treatments. A serendipitous and initially unexplainable clinical finding that a punctate midline dorsal column lesion is effective in eliminating visceral pain, however, has initiated a resurgence of interest in the study of the basic mechanisms of visceral nociception. Clinical and anatomic findings have determined that visceral pain either of thoracic or pelvic origin can be relieved by carefully placed lesions directed at the lateral edge or the medial edge of the gracile fasciculus, respectively. Studies are demonstrating that visceral pain is quite unique from cutaneous pain.

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Year:  2000        PMID: 11060594      PMCID: PMC7879461          DOI: 10.1007/s11916-000-0072-9

Source DB:  PubMed          Journal:  Curr Rev Pain        ISSN: 1069-5850


  55 in total

1.  Role of neurokinin 3 receptors on responses to colorectal distention in the rat: electrophysiological and behavioral studies.

Authors:  V Julia; X Su; L Buéno; G F Gebhart
Journal:  Gastroenterology       Date:  1999-05       Impact factor: 22.682

2.  Acute inflammation differentially alters the activity of two classes of rat spinal visceral nociceptive neurons.

Authors:  T J Ness; G F Gebhart
Journal:  Neurosci Lett       Date:  2000-03-10       Impact factor: 3.046

3.  Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: role of CGRP.

Authors:  V Julia; L Buéno
Journal:  Am J Physiol       Date:  1997-01

4.  Effects of tachykinin receptor antagonists on the rat jejunal distension pain response.

Authors:  P G McLean; R Garcia-Villar; J Fioramonti; L Buéno
Journal:  Eur J Pharmacol       Date:  1998-03-26       Impact factor: 4.432

5.  Is there a pathway in the posterior funiculus that signals visceral pain?

Authors:  R M Hirshberg; E D Al-Chaer; N B Lawand; K N Westlund; W D Willis
Journal:  Pain       Date:  1996-10       Impact factor: 6.961

6.  High thoracic midline dorsal column myelotomy for severe visceral pain due to advanced stomach cancer.

Authors:  Y S Kim; S J Kwon
Journal:  Neurosurgery       Date:  2000-01       Impact factor: 4.654

Review 7.  A visceral pain pathway in the dorsal column of the spinal cord.

Authors:  W D Willis; E D Al-Chaer; M J Quast; K N Westlund
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

8.  Fedotozine blocks hypersensitive visceral pain in conscious rats: action at peripheral kappa-opioid receptors.

Authors:  A Langlois; L Diop; N Friese; X Pascaud; J L Junien; S G Dahl; P J Rivière
Journal:  Eur J Pharmacol       Date:  1997-04-18       Impact factor: 4.432

9.  Nucleus gracilis: an integrator for visceral and somatic information.

Authors:  E D Al-Chaer; K N Westlund; W D Willis
Journal:  J Neurophysiol       Date:  1997-07       Impact factor: 2.714

10.  Decrease in gastric sensitivity to distension by 5-HT1A receptor agonists in rats.

Authors:  M L Rouzade; J Fioramonti; L Bueno
Journal:  Dig Dis Sci       Date:  1998-09       Impact factor: 3.199

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  5 in total

Review 1.  History of Spinal Cord "Pain" Pathways Including the Pathways Not Taken.

Authors:  Allan Basbaum
Journal:  Front Pain Res (Lausanne)       Date:  2022-06-09

2.  Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.

Authors:  Matthew M Smiley; Ying Lu; Louis P Vera-Portocarrero; Amr Zidan; Karin N Westlund
Journal:  Anesthesiology       Date:  2004-09       Impact factor: 7.892

3.  Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls.

Authors:  C H Wilder-Smith; D Schindler; K Lovblad; S M Redmond; A Nirkko
Journal:  Gut       Date:  2004-11       Impact factor: 23.059

4.  Punctate Midline Myelotomy Reduces Pain Responses in a Rat Model of Lumbar Spine Pain: Evidence that the Postsynaptic Dorsal Column Pathway Conveys Pain from the Axial Spine.

Authors:  Haring J Nauta; Sabrina L McIlwrath; Karin N Westlund
Journal:  Cureus       Date:  2018-03-26

Review 5.  Female reproductive tract pain: targets, challenges, and outcomes.

Authors:  Phillip Jobling; Kate O'Hara; Susan Hua
Journal:  Front Pharmacol       Date:  2014-02-13       Impact factor: 5.810

  5 in total

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