Literature DB >> 11060451

Expression and comparative chromosomal mapping of MKP-5 genes DUSP10/Dusp10.

K Masuda1, H Shima, K Kikuchi, Y Watanabe, Y Matsuda.   

Abstract

We have isolated a mouse cDNA for a novel MAPK phosphatase, designated as MKP-5. Two MKP-5 mRNA transcripts of 3.5 kb and 2.7 kb were detected. The 3.5-kb transcript was expressed in almost all the tissues examined, and was particularly abundant in cerebellum, skeletal muscle, and bone marrow. On the other hand, the 2.7-kb transcript was specifically and highly expressed in testis. The MKP-5 genes (DUSP10/Dusp10) were localized to chr 1q41, Chr 1H5 and chr 13q26 in human, mouse and rat, respectively. They were mapped in regions where conserved linkage homology has been identified among the three species. Copyright 2000 S. Karger AG, Basel.

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Year:  2000        PMID: 11060451     DOI: 10.1159/000015666

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  4 in total

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Authors:  A Kuroiwa; K Tsuchiya; K Matsubara; T Namikawa; Y Matsuda
Journal:  Chromosome Res       Date:  2001       Impact factor: 5.239

2.  Dual-specificity phosphatase 10 is fused to MDS1/EVI1-like gene 1 in a case of acute myelogenous leukemia with der1t1;1(p36.3;q21).

Authors:  Mitsuho Noguchi; Haruko Tashiro; Ryosuke Shirasaki; Moritaka Gotoh; Kazuo Kawasugi; Naoki Shirafuji
Journal:  Int J Hematol       Date:  2007-02       Impact factor: 2.490

3.  Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5.

Authors:  Hao Shi; Mayank Verma; Lei Zhang; Chen Dong; Richard A Flavell; Anton M Bennett
Journal:  J Clin Invest       Date:  2013-04-01       Impact factor: 14.808

4.  Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis.

Authors:  Kisuk Min; Ahmed Lawan; Anton M Bennett
Journal:  Skelet Muscle       Date:  2017-10-18       Impact factor: 4.912

  4 in total

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