Literature DB >> 11058593

Signal peptidase and oligosaccharyltransferase interact in a sequential and dependent manner within the endoplasmic reticulum.

X Chen1, C VanValkenburgh, H Liang, H Fang, N Green.   

Abstract

We demonstrate that the signal peptides of prepro-alpha-factor and preinvertase must be cleaved before Asn-X-Ser/Thr acceptor tripeptides located near the signal peptides of these precursors can be efficiently glycosylated within the endoplasmic reticulum of the yeast Saccharomyces cerevisiae. The data support a model whereby the interaction of a signal peptide with the membrane prevents an acceptor tripeptide juxtaposed to the signal peptide from accessing the oligosaccharyltransferase active site until the signal peptide is cleaved.

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Year:  2000        PMID： 11058593     DOI： 10.1074/jbc.M007723200

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  18 in total

1.  Oligosaccharyltransferase directly binds to ribosome at a location near the translocon-binding site.

Authors:  Yoichiro Harada; Hua Li; Huilin Li; William J Lennarz
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-13       Impact factor: 11.205

2.  Co-translational processing of glycoprotein 3 from equine arteritis virus: N-glycosylation adjacent to the signal peptide prevents cleavage.

Authors:  Anna Karolina Matczuk; Dusan Kunec; Michael Veit
Journal:  J Biol Chem       Date:  2013-10-18       Impact factor: 5.157

Review 3.  Secretory protein biogenesis and traffic in the early secretory pathway.

Authors:  Charles K Barlowe; Elizabeth A Miller
Journal:  Genetics       Date:  2013-02       Impact factor: 4.562

4.  Processing of human cytomegalovirus UL37 mutant glycoproteins in the endoplasmic reticulum lumen prior to mitochondrial importation.

Authors:  Manohara S Mavinakere; Chad D Williamson; Victor S Goldmacher; Anamaris M Colberg-Poley
Journal:  J Virol       Date:  2006-07       Impact factor: 5.103

5.  The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides.

Authors:  Yun Ding; Cosma D Dellisanti; Mi Hee Ko; Cynthia Czajkowski; Luigi Puglielli
Journal:  J Biol Chem       Date:  2014-10-09       Impact factor: 5.157

6.  Surface Glycoproteomic Analysis Reveals That Both Unique and Differential Expression of Surface Glycoproteins Determine the Cell Type.

Authors:  Suttipong Suttapitugsakul; Lindsey D Ulmer; Chendi Jiang; Fangxu Sun; Ronghu Wu
Journal:  Anal Chem       Date:  2019-05-03       Impact factor: 6.986

7.  The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.

Authors:  Andrea Marzi; Armin Akhavan; Graham Simmons; Thomas Gramberg; Heike Hofmann; Paul Bates; Vishwanath R Lingappa; Stefan Pöhlmann
Journal:  J Virol       Date:  2006-07       Impact factor: 5.103

8.  An analysis of amino acid sequences surrounding archaeal glycoprotein sequons.

Authors:  Mehtap Abu-Qarn; Jerry Eichler
Journal:  Archaea       Date:  2007-05       Impact factor: 3.273

9.  Apoptosis-inducing signal sequence mutation in carbonic anhydrase IV identified in patients with the RP17 form of retinitis pigmentosa.

Authors:  George Rebello; Rajkumar Ramesar; Alvera Vorster; Lisa Roberts; Liezle Ehrenreich; Ekow Oppon; Dumisani Gama; Soraya Bardien; Jacquie Greenberg; Giuseppe Bonapace; Abdul Waheed; Gul N Shah; William S Sly
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-16       Impact factor: 11.205

Review 10.  Lectin chaperones help direct the maturation of glycoproteins in the endoplasmic reticulum.

Authors:  Bradley R Pearse; Daniel N Hebert
Journal:  Biochim Biophys Acta       Date:  2009-11-03
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