Literature DB >> 11058405

Area under the curve and bioavailability.

A Rescigno1.   

Abstract

The Area Under the Curve (AUC) is proportional to the fraction absorbed only if the clearance is constant and the concentration uniform; in all other cases the bioavailability cannot be determined by comparing AUCs. Copyright 2000 Academic Press.

Mesh：

Year:  2000        PMID： 11058405     DOI： 10.1006/phrs.2000.0719

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN： 1043-6618            Impact factor:   7.658


  2 in total

1.  Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.

Authors:  Huadong Sun; K Sandy Pang
Journal:  Pharm Res       Date:  2010-04-06       Impact factor: 4.200

2.  Improved Bioavailability of Levodopa Using Floatable Spray-Coated Microcapsules for the Management of Parkinson's Disease.

Authors:  Jong-Suep Baek; Jie Kai Tee; Yi Yun Pang; Ern Yu Tan; Kah Leong Lim; Han Kiat Ho; Say Chye Joachim Loo
Journal:  Neuromolecular Med       Date:  2018-04-25       Impact factor: 3.843
  2 in total

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