Literature DB >> 11056417

N-acetylcysteine.

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Abstract

N-acetylcysteine (NAC) is the acetylated precursor of both the amino acid L-cysteine and reduced glutathione (GSH). Historically it has been used as a mucolytic agent in chronic respiratory illnesses as well as an antidote for hepatotoxicity due to acetaminophen overdose. More recently, animal and human studies of NAC have shown it to be a powerful antioxidant and a potential therapeutic agent in the treatment of cancer, heart disease, HIV infection, heavy metal toxicity, and other diseases characterized by free radical oxidant damage. NAC has also been shown to be of some value in treating Sjogren's syndrome, smoking cessation, influenza, hepatitis C, and myoclonus epilepsy.

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Year:  2000        PMID: 11056417

Source DB:  PubMed          Journal:  Altern Med Rev        ISSN: 1089-5159


  5 in total

1.  N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility.

Authors:  Manish Goswami; Narendra Jawali
Journal:  Antimicrob Agents Chemother       Date:  2010-06-14       Impact factor: 5.191

2.  The Effect of Acetylcysteine on Renal Function in Experimental Models of Cyclophosphamide-and Ifosfamide-Induced Cystitis.

Authors:  Lukasz Dobrek; Klaudia Nalik-Iwaniak; Kinga Fic; Zbigniew Arent
Journal:  Curr Urol       Date:  2020-10-13

Review 3.  N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities.

Authors:  Reza Bavarsad Shahripour; Mark R Harrigan; Andrei V Alexandrov
Journal:  Brain Behav       Date:  2014-01-13       Impact factor: 2.708

4.  Psoriatic arthritis.

Authors:  Kara Fitzgerald; Mark Hyman; Kathie Swift
Journal:  Glob Adv Health Med       Date:  2012-09

Review 5.  Secreted mucins in pseudomyxoma peritonei: pathophysiological significance and potential therapeutic prospects.

Authors:  Afshin Amini; Samar Masoumi-Moghaddam; Anahid Ehteda; David Lawson Morris
Journal:  Orphanet J Rare Dis       Date:  2014-05-05       Impact factor: 4.123

  5 in total

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