Literature DB >> 11056313

Modulation of endometrial transforming growth factor beta (TGFbeta) by tamoxifen.

P L Carmichael1, J C Pole, P Neven.   

Abstract

Transforming growth factor beta (TGFbeta) immunoreactivity was determined in endometria from non-drug-therapy and tamoxifen-treated patients. Sections were scored for pathology and quantity image analysis performed to determine levels of glandular- or fibrosis-associated TGFbeta1. Tamoxifen-treated patients displayed greater levels of endometrial dysplasia and glandular hyperplasia, in addition to a statistically significant (P<0.0001) elevation in gland-associated TGFbeta1 protein.

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Year:  2000        PMID: 11056313     DOI: 10.1016/s0959-8049(00)00220-3

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  2 in total

1.  IGF status is altered by tamoxifen in patients with breast cancer.

Authors:  M J Campbell; J V Woodside; J Secker-Walker; A Titcomb; A J Leathem
Journal:  Mol Pathol       Date:  2001-10

Review 2.  "Iron triangle" of regulating the uterine microecology: Endometrial microbiota, immunity and endometrium.

Authors:  Na Zhu; Xuyan Yang; Qiao Liu; Yahui Chen; Xiaolan Wang; Huanhuan Li; Hong Gao
Journal:  Front Immunol       Date:  2022-08-09       Impact factor: 8.786

  2 in total

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