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Literature DB >> 11056282

The ratio of insulin to C-peptide can be used to make a forensic diagnosis of exogenous insulin overdosage.

H Iwase¹, M Kobayashi, M Nakajima, T Takatori.

Abstract

A 25-year-old man was killed by his lover by an intravenous injection of insulin and then air. We had difficulty in determining whether insulin had really been injected, so we have 18 control cases and proved that the ratio of insulin to C-peptide in a corpse can be used as positive evidence for the insulin overdosage.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2001 PMID： 11056282 DOI： 10.1016/s0379-0738(00)00298-x

Source DB: PubMed Journal: Forensic Sci Int ISSN： 0379-0738 Impact factor: 2.395

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Cited

14 in total

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3. Case files of the Harvard Medical Toxicology Fellowship at Children's Hospital Boston: an insulin overdose.

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10. The Mid-Term Effects of Transit Bipartition with Sleeve Gastrectomy on Glycemic Control, Weight Loss, and Nutritional Status in Patients with Type 2 Diabetes Mellitus: a Retrospective Analysis of a 3-Year Follow-up.

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The ratio of insulin to C-peptide can be used to make a forensic diagnosis of exogenous insulin overdosage.

1. Disorders of glucose metabolism: post mortem analyses in forensic cases--part II.

Review 2. Postmortem chemistry update part I.

3. Case files of the Harvard Medical Toxicology Fellowship at Children's Hospital Boston: an insulin overdose.

4. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients.

5. An electrochemical aptamer-based assay for femtomolar determination of insulin using a screen printed electrode modified with mesoporous carbon and 1,3,6,8-pyrenetetrasulfonate.

6. Insulin priming effect on estradiol-induced breast cancer metabolism and growth.

7. Characteristics of fatal insulin overdoses.

Review 8. From Death to Death Certificate: What do the Dead say?

9. Adipogenic factor-loaded microspheres increase retention of transplanted adipose tissue.

10. The Mid-Term Effects of Transit Bipartition with Sleeve Gastrectomy on Glycemic Control, Weight Loss, and Nutritional Status in Patients with Type 2 Diabetes Mellitus: a Retrospective Analysis of a 3-Year Follow-up.