Literature DB >> 11056201

Expression of microglial response factor-1 in microglia and macrophages following cerebral ischemia in the rat.

H Kato1, S Tanaka, T Oikawa, T Koike, A Takahashi, Y Itoyama.   

Abstract

Microglial response factor-1 is a newly isolated microglial gene, which encodes a Ca(2+) binding protein MRF-1 expressed in microglia and macrophages. We induced 1 h of focal cerebral ischemia or 10 min of global cerebral ischemia in the rat, and investigated the expression of MRF-1 immunoreactivity following ischemia. MRF-1 was present in resting microglia and was upregulated in response to microglial activation. MRF-1 was localized to all the cells of the mononuclear phagocyte system (microglia, monocytes, and perivascular cells) that appeared in the ischemic brain.

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Year:  2000        PMID： 11056201     DOI： 10.1016/s0006-8993(00)02811-0

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

1.  Time dependent changes of striatal interneurons after focal cerebral ischemia in rats.

Authors:  M Sakuma; N Hyakawa; H Kato; T Araki
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3.  Ionized calcium-binding adapter molecule 1 immunoreactive cells change in the gerbil hippocampal CA1 region after ischemia/reperfusion.

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4.  Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene.

Authors:  Heather A Boger; Lawrence D Middaugh; Vandana Zaman; Barry Hoffer; Ann-Charlotte Granholm
Journal:  Brain Res       Date:  2008-09-16       Impact factor: 3.252

5.  Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice.

Authors:  Heather A Boger; Lawrence D Middaugh; Ann-Charlotte Granholm; Jacqueline F McGinty
Journal:  Neurobiol Dis       Date:  2008-12-09       Impact factor: 5.996

6.  Postischemic alterations of BDNF, NGF, HSP 70 and ubiquitin immunoreactivity in the gerbil hippocampus: pharmacological approach.

Authors:  Toshiki Himeda; Hiroko Tounai; Natsumi Hayakawa; Tsutomu Araki
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Journal:  BMB Rep       Date:  2016-11       Impact factor: 4.778

8.  Tat-Biliverdin Reductase A Exerts a Protective Role in Oxidative Stress-Induced Hippocampal Neuronal Cell Damage by Regulating the Apoptosis and MAPK Signaling.

Authors:  Sang Jin Kim; Min Jea Shin; Dae Won Kim; Hyeon Ji Yeo; Eun Ji Yeo; Yeon Joo Choi; Eun Jeong Sohn; Kyu Hyung Han; Jinseu Park; Keun Wook Lee; Jong Kook Park; Yong-Jun Cho; Duk-Soo Kim; Won Sik Eum; Soo Young Choi
Journal:  Int J Mol Sci       Date:  2020-04-11       Impact factor: 5.923
  8 in total

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