Literature DB >> 11056080

Pathophysiologic role of selectins and their ligands in ischemia reperfusion injury.

F Chamoun1, M Burne, M O'Donnell, H Rabb.   

Abstract

Research findings are unveiling the potential role of leukocytes and leukocyte adhesion molecules such as selectins in ischemia-reperfusion injury (IRI). "Anti-adhesion" therapy using selectin blocking agents may represent a new approach to treatment of the many diverse clinical disorders in which ischemia-reperfusion occurs, including transplantation, reperfusion after thrombotic events and shock. In this paper we review the pathophysiology of IRI, the different types of selectins and selectin ligands, the clinical implications of selectin blockade in different organs with IRI, and new insights into mechanism of action.

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Year:  2000        PMID： 11056080     DOI： 10.2741/chamoun

Source DB:  PubMed          Journal:  Front Biosci        ISSN： 1093-4715


  17 in total

1.  Selective induction of cell adhesion molecules by proinflammatory mediators in human cardiac microvascular endothelial cells in culture.

Authors:  Jun Yan; Adrian D Nunn; Regi Thomas
Journal:  Int J Clin Exp Med       Date:  2010-10-23

Review 2.  Tissue damage and oxidant/antioxidant balance.

Authors:  Abdullah Kisaoglu; Bunyamin Borekci; O Erkan Yapca; Habib Bilen; Halis Suleyman
Journal:  Eurasian J Med       Date:  2013-02

3.  Loss of L-selectin-guided CD8+ , but not CD4+ , cells protects against ischemia reperfusion injury in a steatotic liver.

Authors:  Vasantha L Kolachala; Sirish Palle; Ming Shen; Alayna Feng; Dmitry Shayakhmetov; Nitika A Gupta
Journal:  Hepatology       Date:  2017-09-04       Impact factor: 17.425

Review 4.  Cell adhesion molecules in chemically-induced renal injury.

Authors:  Walter C Prozialeck; Joshua R Edwards
Journal:  Pharmacol Ther       Date:  2007-01-23       Impact factor: 12.310

5.  The antioxidant effects of pomegranate extract on local and remote organs in a mesenteric ischemia and reperfusion model.

Authors:  Elif Kılıç; Ahmet Türkoğlu; Ayşenur Keleş; Aysun Ekinci; Sıddıka Kesgin; Metehan Gümüş
Journal:  Redox Rep       Date:  2016-03-10       Impact factor: 4.412

6.  P-selectin expression in cold preserved kidneys in University of Wisconsin and histidine-tryptophan-ketoglutarate solutions.

Authors:  Dawit Worku; Sebastian Laluf; Jennifer McGee; Monica Goswami; Keith VanMeter; Douglas P Slakey
Journal:  J Surg Res       Date:  2009-10-01       Impact factor: 2.192

7.  Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways.

Authors:  Magdy Mahmoud-Awny; Ahmed S Attia; Mohamed F Abd-Ellah; Hanan Salah El-Abhar
Journal:  PLoS One       Date:  2015-07-21       Impact factor: 3.240

8.  Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis.

Authors:  Cimen Gülben Olguner; Uğur Koca; Emel Altekin; Bekir Uğur Ergür; Seden Duru; Pelin Girgin; Aydin Taşdöğen; Kerim Gündüz; Seda Güzeldağ; Muhammed Akkuş; Serap Cilaker Micili
Journal:  Exp Ther Med       Date:  2013-04-02       Impact factor: 2.447

9.  Protective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb.

Authors:  Kazuichiro Hori; Masaya Tsujii; Takahiro Iino; Haruhiko Satonaka; Takeshi Uemura; Koji Akeda; Masahiro Hasegawa; Atsumasa Uchida; Akihiro Sudo
Journal:  BMC Musculoskelet Disord       Date:  2013-03-27       Impact factor: 2.362

10.  The Effect of Etoricoxib on Hepatic Ischemia-Reperfusion Injury in Rats.

Authors:  Celalettin Semih Kunak; Osman Kukula; Emre Mutlu; Fatma Genç; Gülçer Güleç Peker; Ufuk Kuyrukluyıldız; Orhan Binici; Durdu Altuner; Hamit Hakan Alp
Journal:  Oxid Med Cell Longev       Date:  2015-07-05       Impact factor: 6.543
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