Literature DB >> 11055673

Amantadine monotherapy of chronic hepatitis C patients infected with genotype lb.

H Senturk1, A Mert, M Akdogan, F Tabak, G Basaran, S Turkoglu, G Ozbay, S Badur.   

Abstract

We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype b. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA. We conclude that amantadine monotherapy is not effective in CHC.

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Year:  2000        PMID: 11055673     DOI: 10.1080/003655400458965

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  5 in total

1.  Retreatment of patients with chronic hepatitis C not responding to interferon/ribavirin combination therapy with daily interferon plus ribavirin plus amantadine.

Authors:  Rudolf E Stauber; Harald Hofer; Franz Hackl; Kurt Schütze; Christian Datz; Karin Hegenbarth; Wolfgang Jessner; Petra Steindl-Munda; Ferenci Peter
Journal:  Wien Klin Wochenschr       Date:  2004-08-31       Impact factor: 1.704

Review 2.  Viral determinants of resistance to treatment in patients with hepatitis C.

Authors:  Anette Wohnsland; Wolf Peter Hofmann; Christoph Sarrazin
Journal:  Clin Microbiol Rev       Date:  2007-01       Impact factor: 26.132

3.  Amantadine's viral kinetics in chronic hepatitis C infection.

Authors:  Juliana Chan; Kenneth O'Riordan; Thelma E Wiley
Journal:  Dig Dis Sci       Date:  2002-02       Impact factor: 3.199

Review 4.  Amantadine for chronic hepatitis c: a magic bullet or yet another dead duck?

Authors:  A Craxi; O Lo Lacono
Journal:  J Hepatol       Date:  2001-10       Impact factor: 25.083

Review 5.  Amantadine in treatment of chronic hepatitis C virus infection?

Authors:  J K Lim; D Wooten; R Siegel; R C Cheung
Journal:  J Viral Hepat       Date:  2005-09       Impact factor: 3.728

  5 in total

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