| Literature DB >> 11055361 |
A S Jørgensen1, P Jacobsen, L B Christiansen, P S Bury, A Kanstrup, S M Thorpe, L Naerum, K Wassermann.
Abstract
A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen.Entities:
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Year: 2000 PMID： 11055361 DOI： 10.1016/s0960-894x(00)00474-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823