Literature DB >> 11053855

Crystallization and preliminary X-ray analysis of CTLA-4 (CD152) membrane-external domain.

C Y Chang1, W H Fenderson, T B Lavoie, R J Peach, H M Einspahr, S Sheriff.   

Abstract

CTLA-4 (CD152) is involved in T-lymphocyte co-stimulatory pathways modulating both humoral and cellular immune response. The membrane-external domain has been prepared and crystallized. The unit-cell parameters are a = b = 43, c = 143 A with the symmetry of space group P3(1)21 or its enantiomer and the crystals diffract to 2. 7 A resolution at synchrotron beamlines.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11053855     DOI： 10.1107/s0907444900010738

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN： 0907-4449


  2 in total

1.  Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering.

Authors:  Chao Yu; Andreas F-P Sonnen; Roger George; Benoit H Dessailly; Loren J Stagg; Edward J Evans; Christine A Orengo; David I Stuart; John E Ladbury; Shinji Ikemizu; Robert J C Gilbert; Simon J Davis
Journal:  J Biol Chem       Date:  2010-12-14       Impact factor: 5.157

2.  Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.

Authors:  Chao Yu; Max Crispin; Andreas F-P Sonnen; David J Harvey; Veronica T Chang; Edward J Evans; Christopher N Scanlan; David I Stuart; Robert J C Gilbert; Simon J Davis
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2011-06-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.