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Literature DB >> 11053801

Prevention and management of mucositis in patients with cancer.

Abstract

This review summarises the large number of locally and systemically applied preventive and therapeutic interventions of mucositis in patients with cancer. The need for further elucidation of the pathophysiology and for optimisation of trial methodology is emphasised. Data from trials in animal models and preliminary data in patients indicate that cytokines such as interleukin-1, interleukin-11, TGF-beta 3 and keratinocyte growth factor could reduce the incidence of mucositis. Other potentially useful agents are the angiogenesis-inhibiting drug thalidomide, the cytoprotector amifostine and the pineal hormone melatonin.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2000 PMID： 11053801 DOI： 10.1016/s0924-8579(00)00232-6

Source DB: PubMed Journal: Int J Antimicrob Agents ISSN： 0924-8579 Impact factor: 5.283

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Cited

7 in total

1. A mucoadhesive thermosensitive hydrogel containing erythropoietin as a potential treatment in oral mucositis: in vitro and in vivo studies.

Authors: Mahboubeh Rezazadeh; Niloofar Jafari; Vajihe Akbari; Marjan Amirian; Majid Tabbakhian; Mohsen Minaiyan; Mahboubeh Rostami
Journal: Drug Deliv Transl Res Date: 2018-10 Impact factor: 4.617

2. High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers.

Authors: Hadley Sharp; John C Morris; Carter Van Waes; David Gius; Theresa Cooley-Zgela; Anurag K Singh
Journal: Am J Clin Oncol Date: 2008-12 Impact factor: 2.339

Prevention and management of mucositis in patients with cancer.

1. A mucoadhesive thermosensitive hydrogel containing erythropoietin as a potential treatment in oral mucositis: in vitro and in vivo studies.

2. High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers.

3. LED and laser photobiomodulation in the prevention and treatment of oral mucositis: experimental study in hamsters.

Review 4. Prevention and management of mucositis in patients with cancer: a review article.

5. Oral mucositis in children suffering from acute lymphoblastic leukaemia.

Review 6. Oral complications and management strategies for patients undergoing cancer therapy.

7. Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia.