Literature DB >> 11053724

Effect of concomitant digoxin and carvedilol therapy on mortality and morbidity in patients with chronic heart failure.

E J Eichhorn1, M A Lukas, B Wu, N Shusterman.   

Abstract

We retrospectively performed stepwise logistic regression analysis on 1,509 patients with chronic heart failure in 4 multicenter United States studies and 1 Australia-New Zealand study to examine the effect of digoxin in patients randomized to carvedilol or placebo. Patients receiving digoxin had more advanced heart failure, the incidence of hospitalization for any cause and the combination of all-cause death and all-cause hospitalization were the same in the digoxin versus no-digoxin groups.

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Year:  2000        PMID： 11053724     DOI： 10.1016/s0002-9149(00)01146-2

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  10 in total

1.  Low-Dose Digoxin and Reduction in Mortality and Morbidity in Heart Failure.

Authors:  Ali Ahmed; Finn Waagstein
Journal:  Int J Cardiol       Date:  2009-07-24       Impact factor: 4.164

2.  Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial.

Authors:  Ali Ahmed; Michael W Rich; Thomas E Love; Donald M Lloyd-Jones; Inmaculada B Aban; Wilson S Colucci; Kirkwood F Adams; Mihai Gheorghiade
Journal:  Eur Heart J       Date:  2005-12-08       Impact factor: 29.983

Review 3.  Current issues regarding beta-adrenergic blockade in patients with congestive heart failure: patient selection, nonselective versus selective blockade, management of adverse effects, and indications for withdrawal of therapy.

Authors:  R Moskowitz; M Kukin
Journal:  Curr Cardiol Rep       Date:  1999-05       Impact factor: 2.931

4.  Digoxin use and lower risk of 30-day all-cause readmission in older patients with heart failure and reduced ejection fraction receiving β-blockers.

Authors:  Phillip H Lam; Poonam Bhyan; Cherinne Arundel; Daniel J Dooley; Helen M Sheriff; Selma F Mohammed; Gregg C Fonarow; Charity J Morgan; Wilbert S Aronow; Richard M Allman; Finn Waagstein; Ali Ahmed
Journal:  Clin Cardiol       Date:  2018-03-22       Impact factor: 2.882

5.  Effects of digoxin at low serum concentrations on mortality and hospitalization in heart failure: a propensity-matched study of the DIG trial.

Authors:  Ali Ahmed; Bertram Pitt; Shahbudin H Rahimtoola; Finn Waagstein; Michel White; Thomas E Love; Eugene Braunwald
Journal:  Int J Cardiol       Date:  2007-03-23       Impact factor: 4.164

6.  Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrations.

Authors:  Ali Ahmed
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2007-03       Impact factor: 6.053

7.  Effectiveness of digoxin in reducing one-year mortality in chronic heart failure in the Digitalis Investigation Group trial.

Authors:  Ali Ahmed; Finn Waagstein; Bertram Pitt; Michel White; Faiez Zannad; James B Young; Shahbudin H Rahimtoola
Journal:  Am J Cardiol       Date:  2008-10-23       Impact factor: 2.778

8.  Effects of discontinuation of digoxin versus continuation at low serum digoxin concentrations in chronic heart failure.

Authors:  Ali Ahmed; Giovanni Gambassi; Michael T Weaver; James B Young; William H Wehrmacher; Michael W Rich
Journal:  Am J Cardiol       Date:  2007-06-06       Impact factor: 2.778

Review 9.  Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data.

Authors:  Oliver J Ziff; Deirdre A Lane; Monica Samra; Michael Griffith; Paulus Kirchhof; Gregory Y H Lip; Richard P Steeds; Jonathan Townend; Dipak Kotecha
Journal:  BMJ       Date:  2015-08-30

Review 10.  GDMT for heart failure and the clinician's conundrum.

Authors:  Padmaraj Samarendra
Journal:  Clin Cardiol       Date:  2019-09-16       Impact factor: 2.882
  10 in total

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