Literature DB >> 11053714

Meta-analysis of the association of platelet glycoprotein IIIa PlA1/A2 polymorphism with myocardial infarction.

M M Zhu1, J Weedon, L T Clark.   

Abstract

This meta-analysis examined all the published reports up to October 1999 that studied the association between PlA2 polymorphism of platelet glycoprotein IIIa gene and myocardial infarction. The PlA2 polymorphism was not found to be associated with an increased risk of myocardial infarction, either overall or in selected subgroups, which were patients with premature disease onset (age < or = 60 years), first acute myocardial infarction, and patients who were men, women, and exclusively Caucasian.

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Year:  2000        PMID: 11053714     DOI: 10.1016/s0002-9149(00)01136-x

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  15 in total

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Authors:  Christian Meisel; José A López; Karl Stangl
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Review 2.  The PlA1/A2 polymorphism of glycoprotein IIIa in relation to efficacy of antiplatelet drugs: a systematic review and meta-analysis.

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Journal:  Br J Clin Pharmacol       Date:  2014-03       Impact factor: 4.335

Review 3.  Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions.

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5.  Platelet glycoprotein IIIA PIA1/A2 polymorphism in young patients with ST elevation myocardial infarction and idiopathic ischemic stroke.

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6.  Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study.

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7.  Platelet glycoprotein IIIA PIA2 polymorphism is associated with ST elevation acute myocardial infarction in young Mexican population.

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8.  The GPIIIA PlA2 polymorphism is associated with an increased risk of cardiovascular adverse events.

Authors:  Gennaro Galasso; Gaetano Santulli; Federico Piscione; Roberta De Rosa; Valentina Trimarco; Raffaele Piccolo; Salvatore Cassese; Guido Iaccarino; Bruno Trimarco; Massimo Chiariello
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Review 9.  Integrin αIIbβ3: from discovery to efficacious therapeutic target.

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10.  Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction.

Authors:  Joshua W Knowles; Huijan Wang; Haruka Itakura; Audrey Southwick; Richard M Myers; Carlos Iribarren; Stephen P Fortmann; Alan S Go; Thomas Quertermous; Mark A Hlatky
Journal:  Am Heart J       Date:  2007-12       Impact factor: 4.749

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