Literature DB >> 1105111

Plasma phenytoin levels produced by various phenytoin preparations.

L N Sansom, W J O'Reilly, C W Wiseman, L M Stern, J Derham.   

Abstract

A cross-over study was conducted to compare the plasma phenytoin levels produced by different phenytoin preparations available in Australia. The preparations were found not to be equivalent, a liquid suspension product producing higher levels compared with capsule and tablet formulations. The clinical significance and possible explantation are discussed.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1105111

Source DB:  PubMed          Journal:  Med J Aust        ISSN： 0025-729X            Impact factor:   7.738


  5 in total

Review 1.  Is generic prescribing acceptable in epilepsy?

Authors:  F M Besag
Journal:  Drug Saf       Date:  2000-09       Impact factor: 5.606

2.  Rate of phenytoin accumulation in man: a simulation study.

Authors:  T M Ludden; J P Allen; L W Schneider; S A Stavchansky
Journal:  J Pharmacokinet Biopharm       Date:  1978-10

3.  Bioavailability and dissolution of proprietary and generic formulations of phenytoin.

Authors:  I Soryal; A Richens
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-08       Impact factor: 10.154

4.  Impact of generic substitution of anticonvulsants on the treatment of epilepsy.

Authors:  A Richens
Journal:  CNS Drugs       Date:  1997-08       Impact factor: 5.749

5.  Bioavailability of three phenytoin preparations in healthy subjects and in epileptics.

Authors:  B Rambeck; H E Boenigk; E Stenzel
Journal:  Eur J Clin Pharmacol       Date:  1977-12-02       Impact factor: 2.953
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.