Literature DB >> 11050268

Resource implications of patients with multidrug resistant tuberculosis.

V L White1, J Moore-Gillon.   

Abstract

BACKGROUND: Multidrug resistant tuberculosis (MDR TB) requires a complex drug regimen and lengthy multidisciplinary care. The financial cost of successful management of each case is potentially large.
METHODS: The costs of managing nine HIV negative patients with pulmonary MDR TB were compared with 18 age group and ethnicity matched controls with fully sensitive disease. Calculations included: cost of outpatient visits and inpatient stays including negative pressure isolation; costs of drug provision and toxicity monitoring; costs of additional procedures and multidisciplinary referrals.
RESULTS: The mean cost of managing a case of pulmonary MDR TB was in excess of 60,000 pounds sterling and for sensitive disease it was 6040 pounds sterling.
CONCLUSIONS: Clinicians and healthcare commissioning authorities may both be underestimating the costs of managing MDR TB, and accordingly the consequences for units dealing with such cases may be serious. Funding of care for MDR TB in the UK requires strategic decisions at regional or governmental level.

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Mesh:

Year:  2000        PMID: 11050268      PMCID: PMC1745633          DOI: 10.1136/thorax.55.11.962

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  1 in total

Review 1.  Treatment of multidrug-resistant tuberculosis.

Authors:  M D Iseman
Journal:  N Engl J Med       Date:  1993-09-09       Impact factor: 91.245

  1 in total
  22 in total

1.  Tuberculosis and social exclusion: new approach is needed.

Authors:  Graham H Bothamley
Journal:  BMJ       Date:  2006-07-22

2.  Screening for tuberculosis: the port of arrival scheme compared with screening in general practice and the homeless.

Authors:  G H Bothamley; J P Rowan; C J Griffiths; M Beeks; M McDonald; E Beasley; C van den Bosch; G Feder
Journal:  Thorax       Date:  2002-01       Impact factor: 9.139

3.  Drug-resistant tuberculosis in sub-saharan Africa.

Authors:  Jeffrey Hafkin; Victoria M Gammino; Joseph J Amon
Journal:  Curr Infect Dis Rep       Date:  2010-01       Impact factor: 3.725

Review 4.  Development of new vaccines and drugs for TB: limitations and potential strategic errors.

Authors:  Ian M Orme
Journal:  Future Microbiol       Date:  2011-02       Impact factor: 3.165

5.  Antibiotic resistant tuberculosis in the United Kingdom: 1993-1999.

Authors:  T Djuretic; J Herbert; F Drobniewski; M Yates; E G Smith; J G Magee; R Williams; P Flanagan; B Watt; A Rayner; M Crowe; M V Chadwick; A M Middleton; J M Watson
Journal:  Thorax       Date:  2002-06       Impact factor: 9.139

6.  Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis.

Authors:  Olga Danilchanka; Claudia Mailaender; Michael Niederweis
Journal:  Antimicrob Agents Chemother       Date:  2008-05-05       Impact factor: 5.191

7.  Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis.

Authors:  Anil Pooran; Helen Booth; Robert F Miller; Geoff Scott; Motasim Badri; Jim F Huggett; Graham Rook; Alimuddin Zumla; Keertan Dheda
Journal:  BMC Pulm Med       Date:  2010-02-22       Impact factor: 3.317

8.  Pan-London tuberculosis services: a service evaluation.

Authors:  Ruth Belling; Susan McLaren; Markella Boudioni; Leslie Woods
Journal:  BMC Health Serv Res       Date:  2012-07-18       Impact factor: 2.655

9.  What is the cost of diagnosis and management of drug resistant tuberculosis in South Africa?

Authors:  Anil Pooran; Elize Pieterson; Malika Davids; Grant Theron; Keertan Dheda
Journal:  PLoS One       Date:  2013-01-18       Impact factor: 3.240

10.  Treatment completion among TB patients returned to the community from a large urban jail.

Authors:  Seijeoung Kim; Kathleen Crittenden
Journal:  J Community Health       Date:  2007-04
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