Literature DB >> 11050258

Randomized controlled trial of supported discharge in patients with exacerbations of chronic obstructive pulmonary disease.

E Skwarska1, G Cohen, K M Skwarski, C Lamb, D Bushell, S Parker, W MacNee.   

Abstract

BACKGROUND: A randomised trial was performed on patients presenting to hospital with an exacerbation of chronic obstructive pulmonary disease (COPD) to compare outcomes in those managed at home with support with those admitted to hospital in the standard manner.
METHODS: Over an 18 month period all patients presenting to the Royal Infirmary of Edinburgh on weekdays (n=718) with a diagnosis of an exacerbation of COPD were assessed for inclusion in the trial. Patients with impaired level of consciousness, acute confusion, acute changes on radiography, or an arterial pH of <7.35 or with other serious medical or social reasons for admission were excluded. Patients randomised to home support were discharged with an appropriate treatment package (antibiotics, corticosteroids, nebulised bronchodilators and, if necessary, home oxygen). They were visited by a nurse the following day and thereafter at intervals of 2-3 days until recovery when they were discharged from follow up. Parallel observations were made on patients allocated to normal hospital admission up to the point of discharge. Patients in both groups were assessed at home eight weeks after the initial assessment.
RESULTS: Among weekday patients 353 (50%) were considered obligatory admissions, 140 (19%) were admitted because of co-morbidity, 17 (2%) because of poor social circumstances, and 24 (3%) did not consent to the trial. The remaining 184 (26%) were randomised (2:1) either to home support or to a standard hospital admission. The median time to discharge was 7 days for the home support group and 5 days for the admitted group (p<0.01); 25% of the home support group and 34% of the admitted group were readmitted before the final assessment at eight weeks (p>0.05). There were no significant differences between the groups in attendances by GPs and carers or in health status measured eight weeks after the initial assessment. Satisfaction with the service was good. The mean total health service cost per patient was estimated as 877 pounds sterling for the home support group and 1753 pounds sterling for the admitted group.
CONCLUSIONS: This study shows that home supported discharge is a well tolerated, safe, and economic alternative to hospital admission for a proportion of patients referred to hospital for admission for an exacerbation of COPD.

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Year:  2000        PMID: 11050258      PMCID: PMC1745644          DOI: 10.1136/thorax.55.11.907

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  2 in total

1.  A measure of quality of life for clinical trials in chronic lung disease.

Authors:  G H Guyatt; L B Berman; M Townsend; S O Pugsley; L W Chambers
Journal:  Thorax       Date:  1987-10       Impact factor: 9.139

2.  Home treatment of exacerbations of chronic obstructive pulmonary disease by an acute respiratory assessment service.

Authors:  J H Gravil; O A Al-Rawas; M M Cotton; U Flanigan; A Irwin; R D Stevenson
Journal:  Lancet       Date:  1998-06-20       Impact factor: 79.321

  2 in total
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1.  Respiratory day hospital: a novel approach to acute respiratory care.

Authors:  K Schwartzman; G Duquette; M Zaoudé; M J Dion; M A Lagacé; J Poitras; M G Cosio
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2.  [Home care as an alternative to conventional hospital admission].

Authors:  Joan Escarrabill
Journal:  Aten Primaria       Date:  2002-09-30       Impact factor: 1.137

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Authors:  David Price; Martin Duerden
Journal:  BMJ       Date:  2003-05-17

Review 4.  Management of an acute exacerbation of copd: are we ignoring the evidence?

Authors:  M K Johnson; R D Stevenson
Journal:  Thorax       Date:  2002-10       Impact factor: 9.139

5.  Staffing by numbers in the NHS.

Authors:  Fiona Moss
Journal:  BMJ       Date:  2002-08-31

6.  Socioeconomic disparities in the use of home health services in a medicare managed care population.

Authors:  Vicki A Freedman; Jeannette Rogowski; Steven L Wickstrom; John Adams; Jonas Marainen; José J Escarce
Journal:  Health Serv Res       Date:  2004-10       Impact factor: 3.402

Review 7.  COPD exacerbations.5: management.

Authors:  R Rodríguez-Roisin
Journal:  Thorax       Date:  2006-06       Impact factor: 9.139

8.  Intermediate care--Hospital-at-Home in chronic obstructive pulmonary disease: British Thoracic Society guideline.

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Journal:  Thorax       Date:  2006-11-07       Impact factor: 9.139

9.  Measurement of physiological recovery from exacerbation of chronic obstructive pulmonary disease using within-breath forced oscillometry.

Authors:  Martin K Johnson; Malcolm Birch; Roger Carter; John Kinsella; Robin D Stevenson
Journal:  Thorax       Date:  2006-11-14       Impact factor: 9.139

10.  The impact of home hospitalization on healthcare costs of exacerbations in COPD patients.

Authors:  Jaume Puig-Junoy; Alejandro Casas; Jaume Font-Planells; Joan Escarrabill; Carme Hernández; Jordi Alonso; Eva Farrero; Gemma Vilagut; Josep Roca
Journal:  Eur J Health Econ       Date:  2007-01-13
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