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Literature DB >> 11049922

Thromboelastography identifies sex-related differences in coagulation.

H J Gorton¹, E R Warren, N A Simpson, G R Lyons, M O Columb.

Abstract

UNLABELLED: Thromboelastography is an in vitro, point-of-care monitor of whole blood coagulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to female sex hormones. The aim of the study was to determine if sex, in addition to pregnancy, affected thromboelastography variables by studying male and female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P:<0.01) differences in sex, with a significant (P: < 0. 0001) trend of increasing whole blood coagulability from men through nonpregnant to pregnant women. The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men. IMPLICATIONS: The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.

Entities: Disease Species

Mesh：

Year: 2000 PMID： 11049922 DOI： 10.1097/00000539-200011000-00042

Source DB: PubMed Journal: Anesth Analg ISSN： 0003-2999 Impact factor: 5.108

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Cited

16 in total

1. Hemostatic responses to exercise, dehydration, and simulated bleeding in heat-stressed humans.

Authors: Matthew A Borgman; Morten Zaar; James K Aden; Zachary J Schlader; Daniel Gagnon; Eric Rivas; Jena Kern; Natalie J Koons; Victor A Convertino; Andrew P Cap; Craig Crandall
Journal: Am J Physiol Regul Integr Comp Physiol Date: 2018-09-19 Impact factor: 3.619

2. Trauma Resuscitation Consideration: Sex Matters.

Authors: Julia R Coleman; Ernest E Moore; Jason M Samuels; Mitchell J Cohen; Angela Sauaia; Joshua J Sumislawski; Arsen Ghasabyan; James G Chandler; Anirban Banerjee; Christopher C Silliman; Erik D Peltz
Journal: J Am Coll Surg Date: 2019-01-21 Impact factor: 6.113

Review 3. Influence of hydroxyethyl starch (HES) 130/0.4 on hemostasis as measured by viscoelastic device analysis: a systematic review.

Authors: Christiane S Hartog; Dorit Reuter; Wolfgang Loesche; Michael Hofmann; Konrad Reinhart
Journal: Intensive Care Med Date: 2011-10-12 Impact factor: 17.440

4. Female platelets have distinct functional activity compared with male platelets: Implications in transfusion practice and treatment of trauma-induced coagulopathy.

Authors: Julia R Coleman; Ernest E Moore; Marguerite R Kelher; Jason M Samuels; Mitchell J Cohen; Angela Sauaia; Anirban Banerjee; Christopher C Silliman; Erik D Peltz
Journal: J Trauma Acute Care Surg Date: 2019-11 Impact factor: 3.313

Thromboelastography identifies sex-related differences in coagulation.

1. Hemostatic responses to exercise, dehydration, and simulated bleeding in heat-stressed humans.

2. Trauma Resuscitation Consideration: Sex Matters.

Review 3. Influence of hydroxyethyl starch (HES) 130/0.4 on hemostasis as measured by viscoelastic device analysis: a systematic review.

4. Female platelets have distinct functional activity compared with male platelets: Implications in transfusion practice and treatment of trauma-induced coagulopathy.

5. Thromboelastography values from pigtail macaques ( Macaca nemestrina): effects of age and sex.

6. Sex-based differences in transfusion need after severe injury: Findings of the PROPPR study.

7. Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix.

8. The effects of 2-chloroprocaine on coagulation and fibrinolysis in the parturient: an in vitro study.

Review 9. Coagulopathy: its pathophysiology and treatment in the injured patient.

10. Hypercoagulability in pregnant trauma patients.