| Literature DB >> 11049218 |
M J Salgueiro1, M Zubillaga, A Lysionek, G Cremaschi, C G Goldman, R Caro, T De Paoli, A Hager, R Weill, J Boccio.
Abstract
The essentiality of zinc for humans was first documented by Prasad in the 1960s. The main clinical manifestations associated with zinc deficiency are growth retardation, hypogonadism, diarrhea, and increased susceptibility to infectious diseases. Thus, in the past 25 yr, there was an increased interest of researchers in studying the role of zinc in human immunity. Although mechanistic research has been carried out using animal models, there are several studies in humans with similar results. This work is an attempt to review the information available in this field to understand the important role that zinc plays in the normal development and function of the immune system.Entities:
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Year: 2000 PMID： 11049218 DOI： 10.1385/BTER:76:3:193
Source DB: PubMed Journal: Biol Trace Elem Res ISSN： 0163-4984 Impact factor: 3.738