Literature DB >> 11048395

Prevalence of long-term use of medicines with prolonged oral clearance in the elderly: a survey in north east England.

A Maguire1, W Baqir.   

Abstract

AIM: To determine the prevalence of long-term use by the elderly of prescribed and over-the-counter (OTC) medicines with prolonged oral clearance (POC), with regard to sugars content, dose form and therapeutic groups of medicines used. DESIGN AND
SETTING: Two cross-sectional observational surveys in ten general medical practices in north-east England during 1996.
METHODS: Computerised patient records of all elderly patients (aged 60 years and over) were surveyed for prescribed medicines use. Within these practices, 50% of elderly patients registered with ten general medical practitioners were surveyed by postal questionnaire to assess over-the-counter (OTC) medicines use.
RESULTS: Of 20,731 elderly patients registered, prevalence of use of prescribed prolonged oral clearance (POC) medicines was 9.8% (95% CI: 8.2%, 11.3%) and use in females aged 75 years and older was significantly more likely (P < 0.0001). Of 2,796 prescribing instances (PIs) for 143 POC medicines used long-term, 53% were gastrointestinal and 72% were sugars-free; however, 82% of 542 PIs for generic liquids were sugars-containing compared with 8% of 685 PIs for proprietary liquid oral medicines. Of 1,532 elderly respondents to a postal questionnaire, 17 were using 13 different OTC medicines with POC regularly and long-term (mean prevalence; 1.1%). Of the 17 instances of regular long-term use of OTC medicines, 59% were sugars-free.
CONCLUSIONS: Prescribed medicines represent the bulk of regular, long-term medicines use in the elderly. Generic prescribing is more likely to result in sugars-containing medicines being dispensed. Generic medicines manufacturers must be encouraged to provide sugars-free alternatives to POC medicines used long-term, and health professionals should be vigilant when prescribing and dispensing these medicines to the increasingly dentate elderly.

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Year:  2000        PMID: 11048395     DOI: 10.1038/sj.bdj.4800741

Source DB:  PubMed          Journal:  Br Dent J        ISSN: 0007-0610            Impact factor:   1.626


  1 in total

1.  Erosive potential of sugar free and sugar containing pediatric medicines given regularly and long term to children.

Authors:  Ruchi Arora; Utsav Mukherjee; Vivek Arora
Journal:  Indian J Pediatr       Date:  2011-08-10       Impact factor: 1.967

  1 in total

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