Literature DB >> 11043130

[Pathological fracture in primary malignant bone tumors].

F Zeifang1, D Sabo, V Ewerbeck.   

Abstract

Retrospective analysis of 30 patients with pathological fracture out of 336 patients with primary malignant bone tumors should demonstrate the influence a pathologic fracture and the form of surgical therapy have on the survival rate. In 25 out of 30 patients a fracture led to diagnosis of the disease. Pathological fractures occurred cumulatively by malignant fibrous histiocytoma of the bone and in tumor stages IIb and III. Surgery was performed on 26 out of 30 patients (12 ablative therapies, 14 reconstructive therapies). The mortality risk for patients with pathological fractures was more than double the risk for patients without pathological fractures (P = 0.0062). When performed correctly, reconstructive therapy does not influence the survival rate.

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Year:  2000        PMID: 11043130     DOI: 10.1007/s001040051188

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  5 in total

Review 1.  [Biopsy of musculoskeletal tumors : Complications and avoidable errors].

Authors:  D Winkler; H Fritzsche; K-D Schaser; C Hofbauer
Journal:  Orthopade       Date:  2020-02       Impact factor: 1.087

2.  Two case-reports of the limb salvage treatment of osteosarcoma consolidated with obvious pathological fractures.

Authors:  Q Cui; D F Li; C Liu; J Guo; S B Liu; Y S Liu; J M Zhai; Yanjun Zeng
Journal:  Pathol Oncol Res       Date:  2011-01-09       Impact factor: 3.201

3.  The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours.

Authors:  Babak Moradi; Anita Zahlten-Hinguranage; Burkhard Lehner; Felix Zeifang
Journal:  Int Orthop       Date:  2009-12-13       Impact factor: 3.075

4.  Meta-analysis of limb salvage versus amputation for treating high-grade and localized osteosarcoma in patients with pathological fracture.

Authors:  Ke Yin; Qiande Liao; DA Zhong; Jie Ding; Bing Niu; Qiupping Long; Dengfeng Ding
Journal:  Exp Ther Med       Date:  2012-08-28       Impact factor: 2.447

Review 5.  A comparative study between limb-salvage and amputation for treating osteosarcoma.

Authors:  Xiaojuan Li; Ya Zhang; Shanshan Wan; Huiling Li; Dongqi Li; Junfeng Xia; Zhongqin Yuan; Mingyan Ren; Shunling Yu; Su Li; Yihao Yang; Lei Han; Zuozhang Yang
Journal:  J Bone Oncol       Date:  2016-01-23       Impact factor: 4.072

  5 in total

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