Literature DB >> 11042468

Life and death of the pancreatic beta cells.

S Bonner-Weir1.   

Abstract

Pancreatic beta cells are responsible for maintaining the body's glucose levels within a very narrow range; their population is dynamic, with compensatory changes to maintain euglycemia. Throughout the lifetime of a mammal, low levels of beta-cell replication and apoptosis are balanced and result in a slowly increasing mass of beta cells. The emphasis in this review is on recent insights on the natural history of the beta cell in a normal pancreas: sources of renewal, survival and changes in differentiation.

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Year:  2000        PMID： 11042468     DOI： 10.1016/s1043-2760(00)00305-2

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  85 in total

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2.  Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.

Authors:  Shouhong Xuan; Tadahiro Kitamura; Jun Nakae; Katerina Politi; Yoshiaki Kido; Peter E Fisher; Manrico Morroni; Saverio Cinti; Morris F White; Pedro L Herrera; Domenico Accili; Argiris Efstratiadis
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

3.  Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.

Authors:  Juan C Alvarez-Perez; Taylor C Rosa; Gabriella P Casinelli; Shelley R Valle; Jayalakshmi Lakshmipathi; Carolina Rosselot; Francisco Rausell-Palamos; Rupangi C Vasavada; Adolfo García-Ocaña
Journal:  Mol Endocrinol       Date:  2014-12

Review 4.  Pancreatic stem cells: from possible to probable.

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Journal:  Proc Natl Acad Sci U S A       Date:  2005-10-06       Impact factor: 11.205

Review 7.  Cell transplantation for diabetes.

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Authors:  Brad P Barnett; Jesús Ruiz-Cabello; Partha Hota; Robert Liddell; Piotr Walczak; Valerie Howland; Vadappuram P Chacko; Dara L Kraitchman; Aravind Arepally; Jeff W M Bulte
Journal:  Radiology       Date:  2010-10-22       Impact factor: 11.105

9.  Insulin stimulates primary beta-cell proliferation via Raf-1 kinase.

Authors:  Jennifer L Beith; Emilyn U Alejandro; James D Johnson
Journal:  Endocrinology       Date:  2008-01-17       Impact factor: 4.736

10.  Role of PTP/PTK trans activated insulin-like signalling pathway in regulation of grasshopper (Oedaleus asiaticus) development.

Authors:  Babar Hussain Chang; Boyang Cui; Hidayat Ullah; Shuang Li; Kun Hao; Xiongbing Tu; Guangjun Wang; Xiangqun Nong; Mark Richard McNeill; Xunbing Huang; Zehua Zhang
Journal:  Environ Sci Pollut Res Int       Date:  2019-01-31       Impact factor: 4.223
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