Literature DB >> 11040993

[Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms].

A V Fokin1, P V Afonin, I Iu Mikhaĭlova, I N Tsygannik, T Iu Mareeva, V A Nesmeianov, W Pangborn, N Lee, W Duax, E Siszak, V Z Pletnev.   

Abstract

The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 A resolutions. The spatial structure of the protein and the stereochemistry of its antigen-binding site were analyzed.

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Year:  2000        PMID： 11040993

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN： 0132-3423


  3 in total

1.  Polder maps: improving OMIT maps by excluding bulk solvent.

Authors:  Dorothee Liebschner; Pavel V Afonine; Nigel W Moriarty; Billy K Poon; Oleg V Sobolev; Thomas C Terwilliger; Paul D Adams
Journal:  Acta Crystallogr D Struct Biol       Date:  2017-02-01       Impact factor: 7.652

2.  Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.

Authors:  Vannakambadi K Ganesh; Xiaowen Liang; Joan A Geoghegan; Ana Luisa V Cohen; Nagarajan Venugopalan; Timothy J Foster; Magnus Hook
Journal:  EBioMedicine       Date:  2016-10-01       Impact factor: 8.143

3.  Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state.

Authors:  Hsiang-Ting Lei; Jinming Ma; Silvia Sanchez Martinez; Tamir Gonen
Journal:  Nat Struct Mol Biol       Date:  2018-06-05       Impact factor: 15.369
  3 in total

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