Literature DB >> 11040270

Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition.

G A Curt1, W Breitbart, D Cella, J E Groopman, S J Horning, L M Itri, D H Johnson, C Miaskowski, S L Scherr, R K Portenoy, N J Vogelzang.   

Abstract

PURPOSE: This survey was designed to confirm the prevalence and duration of fatigue in the cancer population and to assess its physical, mental, social, and economic impacts on the lives of patients and caregivers. Patients and Methods. A 25-minute telephone interview was completed with 379 cancer patients having a prior history of chemotherapy. Patients were recruited from a sample of 6, 125 households in the United States identified as having a member with cancer. The median patient age was 62 years, and 79% of respondents were women. Patients reporting fatigue at least a few times a month were asked a series of questions to better describe their fatigue and its impact on quality of life.
RESULTS: Seventy-six percent of patients experienced fatigue at least a few days each month during their most recent chemotherapy; 30% experienced fatigue on a daily basis. Ninety-one percent of those who experienced fatigue reported that it prevented a "normal" life, and 88% indicated that fatigue caused an alteration in their daily routine. Fatigue made it more difficult to participate in social activities and perform typical cognitive tasks. Of the 177 patients who were employed, 75% changed their employment status as a result of fatigue. Furthermore, 65% of patients indicated that their fatigue resulted in their caregivers taking at least one day (mean, 4.5 days) off work in a typical month. Physicians were the health care professionals most commonly consulted (79%) to discuss fatigue. Bed rest/ relaxation was the most common treatment recommendation (37%); 40% of patients were not offered any recommendations.
CONCLUSIONS: Cancer-related fatigue is common among cancer patients who have received chemotherapy and results in substantial adverse physical, psychosocial, and economic consequences for both patients and caregivers. Given the impact of fatigue, treatment options should be routinely considered in the care of patients with cancer.

Entities:  

Mesh:

Year:  2000        PMID: 11040270     DOI: 10.1634/theoncologist.5-5-353

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  325 in total

1.  Fatigue in cancer.

Authors:  G A Curt
Journal:  BMJ       Date:  2001-06-30

2.  Cancer fatigue--more data, less information?

Authors:  Susan B LeGrand
Journal:  Curr Oncol Rep       Date:  2002-07       Impact factor: 5.075

3.  Fatigue and quality of life in breast cancer survivors: temporal courses and long-term pattern.

Authors:  Martina E Schmidt; Jenny Chang-Claude; Alina Vrieling; Judith Heinz; Dieter Flesch-Janys; Karen Steindorf
Journal:  J Cancer Surviv       Date:  2011-12-11       Impact factor: 4.442

4.  Presurgery psychological factors predict pain, nausea, and fatigue one week after breast cancer surgery.

Authors:  Guy H Montgomery; Julie B Schnur; Joel Erblich; Michael A Diefenbach; Dana H Bovbjerg
Journal:  J Pain Symptom Manage       Date:  2010-06       Impact factor: 3.612

Review 5.  ASCPRO recommendations for the assessment of fatigue as an outcome in clinical trials.

Authors:  Andrea M Barsevick; Charles S Cleeland; Donald C Manning; Ann M O'Mara; Bryce B Reeve; Jane A Scott; Jeff A Sloan
Journal:  J Pain Symptom Manage       Date:  2010-06       Impact factor: 3.612

6.  A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.

Authors:  Glenn J Lesser; Doug Case; Nancy Stark; Susan Williford; Jeff Giguere; L Astrid Garino; Michelle J Naughton; Mara Z Vitolins; Mark O Lively; Edward G Shaw
Journal:  J Support Oncol       Date:  2013-03

Review 7.  The role of neuro-immune interactions in cancer-related fatigue: Biobehavioral risk factors and mechanisms.

Authors:  Julienne E Bower
Journal:  Cancer       Date:  2019-01-02       Impact factor: 6.860

8.  Trajectories of fatigue in family caregivers of patients undergoing radiation therapy for prostate cancer.

Authors:  Barbara A Swore Fletcher; Karen L Schumacher; Marylin Dodd; Steven M Paul; Bruce A Cooper; Kathryn Lee; Claudia West; Bradley E Aouizerat; Patrick S Swift; William Wara; Christine Miaskowski
Journal:  Res Nurs Health       Date:  2009-04       Impact factor: 2.228

9.  Fatigue following Paediatric Acquired Brain Injury and its Impact on Functional Outcomes: A Systematic Review.

Authors:  Jake Wilkinson; Nohely Lee Marmol; Celia Godfrey; Harriet Wills; Quirine van Eijndhoven; Edith Nardu Botchway; Nikita Sood; Vicki Anderson; Cathy Catroppa
Journal:  Neuropsychol Rev       Date:  2018-03-19       Impact factor: 7.444

10.  A role for orexin in cytotoxic chemotherapy-induced fatigue.

Authors:  K B Weymann; L J Wood; X Zhu; D L Marks
Journal:  Brain Behav Immun       Date:  2013-11-09       Impact factor: 7.217

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