| Literature DB >> 1103871 |
Abstract
Ionizing radiation induces double-strand breaks in the nuclear DNA of the yeast Saccharomyces cerevisiae with an efficiency of approximately 0.6 X 10(-10) breaks being repaired. Based on the efficiency of break production, the sensitivity of a rad52 mutant, and the absence of radiation-induced recombination in such a mutant, it is proposed that the corresponding gene product may be involved in double-strand break repair. A model involving recombination and DNA synthesis is described for this type of repair.Entities:
Mesh：
Substances：
Year: 1975 PMID： 1103871 DOI： 10.1007/978-1-4684-2898-8_20
Source DB: PubMed Journal: Basic Life Sci ISSN： 0090-5542