| Literature DB >> 11036045 |
A Novelli1, S Fallani, M I Cassetta, S Conti, T Mazzei.
Abstract
The postantibiotic leukocyte enhancement (PALE) of meropenem in vitro in comparison with that of imipenem was evaluated with 24 recently isolated gram-positive and gram-negative strains. In general, pre-exposure to carbapenems (at four times the MIC for 2 h) led to increased polymorphonuclear cell phagocytic killing. The PALE of imipenem was generally significantly less than that observed with meropenem.Entities:
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Year: 2000 PMID: 11036045 PMCID: PMC101625 DOI: 10.1128/AAC.44.11.3174-3176.2000
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191