Literature DB >> 11035766

The nonfunctional allele TCRBV6S1B is strongly associated with Helicobacter pylori infection.

E Kunstmann1, C Hardt, E Elitok, M Harder, S Suerbaum, U Peitz, W Schmiegel, J T Epplen.   

Abstract

To determine genetic susceptibility factors for Helicobacter pylori infection, polymorphic T-cell receptor gene elements were investigated in 203 H. pylori-infected individuals and 180 uninfected individuals (controls). H. pylori infection is highly associated with individuals homozygous for the nonfunctional TCRBV6S1B element (odds ratio = 5.9; chi(2) = 13; P = 0.00032; P value corrected for multiple comparisons [Bonferroni correction] = 0. 00063).

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Year:  2000        PMID： 11035766      PMCID： PMC97740          DOI： 10.1128/IAI.68.11.6493-6495.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  12 in total

1.  The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.

Authors:  L Rowen; B F Koop; L Hood
Journal:  Science       Date:  1996-06-21       Impact factor: 47.728

2.  A simple salting out procedure for extracting DNA from human nucleated cells.

Authors:  S A Miller; D D Dykes; H F Polesky
Journal:  Nucleic Acids Res       Date:  1988-02-11       Impact factor: 16.971

3.  Polymorphism and phylogeny of dinucleotide repeats in human T-cell receptor Vb6 genes.

Authors:  P Charmley; P Concannon
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

Review 4.  Signals and signs for lymphocyte responses.

Authors:  C A Janeway; K Bottomly
Journal:  Cell       Date:  1994-01-28       Impact factor: 41.582

5.  Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype.

Authors:  K B Bamford; X Fan; S E Crowe; J F Leary; W K Gourley; G K Luthra; E G Brooks; D Y Graham; V E Reyes; P B Ernst
Journal:  Gastroenterology       Date:  1998-03       Impact factor: 22.682

6.  HLA and T cell receptor beta-chain DNA polymorphisms identify a distinct subset of patients with pauciarticular-onset juvenile rheumatoid arthritis.

Authors:  P Charmley; B S Nepom; P Concannon
Journal:  Arthritis Rheum       Date:  1994-05

7.  Novel members and germline polymorphisms in the human T-cell receptor Vb6 family.

Authors:  M Gomolka; C Epplen; J Buitkamp; J T Epplen
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

8.  PCR-based genotyping and haplotype analysis of human TCRBV gene segment polymorphisms.

Authors:  P Charmley; P Concannon
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

9.  Immunoprinting: various genes are associated with increased risk to develop rheumatoid arthritis in different groups of adult patients.

Authors:  M Gomolka; H Menninger; J E Saal; E M Lemmel; E D Albert; O Niwa; J T Epplen; C Epplen
Journal:  J Mol Med (Berl)       Date:  1995-01       Impact factor: 4.599

10.  Reduced expression of a human V beta 6.1 T-cell receptor allele.

Authors:  L Luyrink; C A Gabriel; S D Thompson; A A Grom; W P Maksymowych; E Choi; D N Glass
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-15       Impact factor: 11.205
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