Literature DB >> 11034273

Fluconazole-induced convulsions at serum trough concentrations of approximately 80 microg/mL.

K Matsumoto1, K Ueno, H Yoshimura, M Morii, M Takada, T Sawai, K Mitsutake, M Shibakawa.   

Abstract

On the basis of two case reports it is suggested that serious convulsions may occur in patients treated with flucoazole when serum trough concentrations exceed 80 microg/mL. The authors recommend monitoring fluconazole concentrations during high-dose therapy in patients with poor kidney function.

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Year:  2000        PMID: 11034273     DOI: 10.1097/00007691-200010000-00022

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN: 0163-4356            Impact factor:   3.681


  2 in total

1.  Neurological and Psychiatric Adverse Effects of Antimicrobials.

Authors:  Madison K Bangert; Rodrigo Hasbun
Journal:  CNS Drugs       Date:  2019-08       Impact factor: 5.749

2.  Fluconazole Population Pharmacokinetics after Fosfluconazole Administration and Dosing Optimization in Extremely Low-Birth-Weight Infants.

Authors:  Ayano Tanzawa; Jumpei Saito; Kensuke Shoji; Yuka Kojo; Takanori Funaki; Hidehiko Maruyama; Tetsuya Isayama; Yushi Ito; Hidefumi Nakamura; Akimasa Yamatani
Journal:  Microbiol Spectr       Date:  2022-03-10
  2 in total

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