| Literature DB >> 11034151 |
Abstract
We showed how eugenol blocks the synaptic transmission and gave a possible interpretation how it inhibits the excitation-contraction coupling that several authors described previously. Eugenol acts both in the pre- and postsynaptic side of the neurons. It blocks the Ca2+-currents, decreases the membrane potential of the neurons, increases the inward resistance and decreases the GABA, ACh and glutamate evoked excitatory responses in submillimolar concentration.Entities:
Mesh：
Substances：
Year: 2000 PMID： 11034151
Source DB: PubMed Journal: Acta Biol Hung ISSN： 0236-5383