Literature DB >> 11032918

Induction of apoptosis by gallic acid in human stomach cancer KATO III and colon adenocarcinoma COLO 205 cell lines.

K Yoshioka1, T Kataoka, T Hayashi, M Hasegawa, Y Ishi, H Hibasami.   

Abstract

Antitumor effects of gallic acid on human stomach cancer KATO III cells and human colon adenocarcinoma COLO 205 cells were investigated. The exposures of KATO III and COLO 205 cells to gallic acid led to both growth inhibition and induction of apoptosis. Morphological changes showing apoptotic bodies were observed in both the cell lines treated with gallic acid. The fragmentations by gallic acid of DNA to oligonucleosomal-sized fragments, that are characteristics of apoptosis, were observed to be concentration- and time-dependent. These findings suggest that growth inhibitions by gallic acid of KATO III cells and COLO 205 cells result from the apoptosis induced by gallic acid. Thus, gallic acid might be a candidate drug for digestive gut cancer treatment to overcome the resistance to chemotherapeutic drugs.

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Year:  2000        PMID： 11032918     DOI： 10.3892/or.7.6.1221

Source DB:  PubMed          Journal:  Oncol Rep        ISSN： 1021-335X            Impact factor:   3.906


  10 in total

Review 1.  Gallic Acid: A Potential Anti-Cancer Agent.

Authors:  Yuan Jiang; Jin Pei; Yan Zheng; Yu-Jing Miao; Bao-Zhong Duan; Lin-Fang Huang
Journal:  Chin J Integr Med       Date:  2021-11-10       Impact factor: 1.978

2.  Mesoporous Silica Materials Loaded with Gallic Acid with Antimicrobial Potential.

Authors:  Gabriela Petrisor; Denisa Ficai; Ludmila Motelica; Roxana Doina Trusca; Alexandra Cătălina Bîrcă; Bogdan Stefan Vasile; Georgeta Voicu; Ovidiu Cristian Oprea; Augustin Semenescu; Anton Ficai; Mircea Ionut Popitiu; Irina Fierascu; Radu Claudiu Fierascu; Elena Lacramioara Radu; Lilia Matei; Laura Denisa Dragu; Ioana Madalina Pitica; Mihaela Economescu; Coralia Bleotu
Journal:  Nanomaterials (Basel)       Date:  2022-05-12       Impact factor: 5.719

3.  Activation of Casein Kinase II by Gallic Acid Induces BIK-BAX/BAK-Mediated ER Ca++-ROS-Dependent Apoptosis of Human Oral Cancer Cells.

Authors:  Meng-Liang Lin; Shih-Shun Chen
Journal:  Front Physiol       Date:  2017-09-29       Impact factor: 4.566

4.  Gallic acid and curcumin induce cytotoxicity and apoptosis in human breast cancer cell MDA-MB-231.

Authors:  Hassan Moghtaderi; Houri Sepehri; Ladan Delphi; Farnoosh Attari
Journal:  Bioimpacts       Date:  2018-03-05

5.  Synthesis, antiproliferative activity and molecular properties predictions of galloyl derivatives.

Authors:  Marciane Maximo da Silva; Marina Comin; Thiago Santos Duarte; Mary Ann Foglio; João Ernesto de Carvalho; Maria Carmo do Vieira; Anelise Samara Nazari Formagio
Journal:  Molecules       Date:  2015-03-25       Impact factor: 4.411

Review 6.  Gallic Acid and Diabetes Mellitus: Its Association with Oxidative Stress.

Authors:  Yu Xu; Guoyi Tang; Cheng Zhang; Ning Wang; Yibin Feng
Journal:  Molecules       Date:  2021-11-24       Impact factor: 4.411

Review 7.  A comprehensive review on the diverse pharmacological perspectives of Terminalia chebula Retz.

Authors:  Md Rakibul Hassan Bulbul; Mohammad Nizam Uddin Chowdhury; Taslima Anjum Naima; Saad Ahmed Sami; Md Shakil Imtiaj; Nazmul Huda; Md Giash Uddin
Journal:  Heliyon       Date:  2022-08-14

8.  Gallic Acid Induces a Reactive Oxygen Species-Provoked c-Jun NH2-Terminal Kinase-Dependent Apoptosis in Lung Fibroblasts.

Authors:  Chiu-Yuan Chen; Kun-Chieh Chen; Tsung-Ying Yang; Hsiang-Chun Liu; Shih-Lan Hsu
Journal:  Evid Based Complement Alternat Med       Date:  2013-02-20       Impact factor: 2.629

9.  Ethyl gallate induces apoptosis of HL-60 cells by promoting the expression of caspases-8, -9, -3, apoptosis-inducing factor and endonuclease G.

Authors:  Woong-Hyun Kim; Hyun-Ok Song; Hwa-Jung Choi; Ho-Il Bang; Du-Young Choi; Hyun Park
Journal:  Int J Mol Sci       Date:  2012-09-20       Impact factor: 6.208

10.  Sanguisorba officinalis L synergistically enhanced 5-fluorouracil cytotoxicity in colorectal cancer cells by promoting a reactive oxygen species-mediated, mitochondria-caspase-dependent apoptotic pathway.

Authors:  Meng-Ping Liu; Min Liao; Cong Dai; Jie-Feng Chen; Chun-Juan Yang; Ming Liu; Zuan-Guang Chen; Mei-Cun Yao
Journal:  Sci Rep       Date:  2016-09-27       Impact factor: 4.379
  10 in total

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