Literature DB >> 110318

Enumeration of drosophila form II DNA-dependent RNA polymerase initiation sites on Drosophila DNA.

J P Phillips.   

Abstract

The in vitro incorporation of gamma-32P-labeled nucleoside triphosphates into RNA by Drosophila melanogaster form II RNA polymerase from template sites which afford protection from the initiation inhibitor, polyriboinosinic acid (poly [I]), is used as a method for enumerating a specific class of transcription initiation sites on D. melanogaster DNA. Such sites number about 4000 per haploid genome for D. melanogaster. This value is in good agreement with the number of functional genetic units in the D. melanogaster genome as determined by classical cytogenetics.

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Year:  1979        PMID： 110318     DOI： 10.1007/bf00484476

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  18 in total

Review 1.  Eukaryotic nuclear RNA polymerases.

Authors:  P Chambon
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

2.  Functional organization of genetic material as a product of molecular evolution.

Authors:  T Ohta; M Kimura
Journal:  Nature       Date:  1971-09-10       Impact factor: 49.962

3.  Globin mRNA sequences in polyadenylated and nonpolyadenylated nuclear precursor-messenger RNA from avian erythroblasts.

Authors:  G Spohr; G Dettori; V Manzari
Journal:  Cell       Date:  1976-08       Impact factor: 41.582

Review 4.  The selectivity of transcription.

Authors:  M J Chamberlin
Journal:  Annu Rev Biochem       Date:  1974       Impact factor: 23.643

5.  Specificity of sigma-dependent binding of RNA polymerase to DNA.

Authors:  E K Bautz; F A Bautz; E Beck
Journal:  Mol Gen Genet       Date:  1972

6.  Analysis of chromosome 4 in Drosophila melanogaster. II. Ethyl methanesulfonate induced lethals.

Authors:  B Hochman
Journal:  Genetics       Date:  1971-02       Impact factor: 4.562

7.  The size of poly(A)-containing RNAs in Drosophila melanogaster embryos.

Authors:  M M Lamb; C D Laird
Journal:  Biochem Genet       Date:  1976-04       Impact factor: 1.890

8.  The one band-one gene hypothesis: evidence from a cytogenetic analysis of mutant and nonmutant rearrangement breadpoints in Drosophila melanogaster.

Authors:  G Lefevre
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1974

9.  Diversity of RNA sequences in Drosophila melanogaster.

Authors:  S H Turner; C D Laird
Journal:  Biochem Genet       Date:  1973-11       Impact factor: 1.890

10.  Organization and transcription of DNA in chromosomes and mitochondria of Drosophila.

Authors:  C D Laird; W Y Chool; E H Cohen; E Dickson; N Hutchinson; S H Turner
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1974
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  1 in total

1.  Form II DNA-dependent RNA polymerase from Drosophila melanogaster: general in vitro catalytic properties and template interactions.

Authors:  J P Phillips
Journal:  Biochem Genet       Date:  1979-02       Impact factor: 1.890
  1 in total

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