Literature DB >> 1103113

Feprazone compared with indomethacin in the management of rheumatoid arthritis.

R Sturrock, A Isaacs, F D Hart.   

Abstract

A double-blind cross-over trial of feprazone 450 mg daily and indomethacin 75 mg daily was carried out in fourteen patients with rheumatoid arthritis. The analgesic and anti-inflammatory activity was indistinguishable from that of indomethacin under the conditions of the trial. Seven patients expressed a preference for feprazone and four for indomethacin. Feprazone appeared to be well tolerated and free from serious side-effects. These results suggest that feprazone will be a useful drug in the management of rheumatoid arthritis.

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Year:  1975        PMID: 1103113

Source DB:  PubMed          Journal:  Practitioner        ISSN: 0032-6518


  3 in total

1.  Rectal administration of feprazone in healthy volunteers.

Authors:  P Ferrari; C Montanari; P Sala; A Vidi
Journal:  Br J Clin Pharmacol       Date:  1976-04       Impact factor: 4.335

2.  An analysis of the gastro-intestinal side-effects of non-steroidal anti-inflammatory drugs, with particular reference to comparative studies in man and laboratory species.

Authors:  K D Rainsford
Journal:  Rheumatol Int       Date:  1982       Impact factor: 2.631

3.  Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes.

Authors:  Zhusong Huang; Jinfu Lan; Xi Gao
Journal:  ACS Omega       Date:  2021-03-31
  3 in total

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