| Literature DB >> 11030999 |
J I Jiménez1, W Y Yoshida, P J Scheuer, E Lobkovsky, J Clardy, M Kelly.
Abstract
From the dichloromethane/2-propanol (1:1) extract of the Indonesian marine sponge Strepsichordaia aliena, twelve new 20, 24-bishomoscalarane sesterterpenes, honulactones A-L (1-12) were isolated. Molecular structures were secured by spectroscopic methods, accurate mass measurements, and X-ray analysis. Honulactones A (1), B (2), C (3), and D (4) exhibit cytotoxycity against P-388, A-549, HT-29, and MEL-28 (IC(50) 1 microg/mL).Entities:
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Year: 2000 PMID： 11030999 DOI： 10.1021/jo991924b
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354