| Literature DB >> 1103074 |
F E Simons, C W Bierman, A C Sprenkle, K J Simons.
Abstract
The efficacy of dyphlline in prevention of exercise-induced bronchospasm (EIB) was studied in seven subjects. A single 15 mg/kg dose of dyphylline 40 minutes prior to exercise prevented EIB as documented by a significantly smaller mean greatest percent decrease in forced expiratory volume in one second when compared to placebo. Mean serum dyphylline concentrations 40 minutes after a dose of 15 mg/kg were probably in the lower portion of the therapeutic range.Entities:
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Year: 1975 PMID： 1103074
Source DB: PubMed Journal: Pediatrics ISSN： 0031-4005 Impact factor: 7.124